Synthesis of ethyl-3-amino-1-aryl-1H-benzo[f]chromeme-2-carboxylate derivatives promoted by DMAP
An efficient route, convenient and environmentally friendly procedure for the synthesis chromenes derivatives have been developed via a three-component coupling and one-pot reactions of various aromatic aldehyde with malononitrile or ethyl cyanoacetate and phenols in the presence N,N-dimethylpyridin...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Growing Science
2017-05-01
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| Series: | Current Chemistry Letters |
| Subjects: | |
| Online Access: | http://www.growingscience.com/ccl/Vol6/ccl_2017_5.pdf |
| Summary: | An efficient route, convenient and environmentally friendly procedure for the synthesis chromenes derivatives have been developed via a three-component coupling and one-pot reactions of various aromatic aldehyde with malononitrile or ethyl cyanoacetate and phenols in the presence N,N-dimethylpyridin-4-amine (DMAP) in reflux conditions. In simple reaction conditions, the use of DMAP is explored as an easy workup and a green catalyst for the one-pot three-component synthesis ethyl 3-amino-1-aryl-1H-benzo[f]chromene-2-carboxylate derivatives. |
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| ISSN: | 1927-7296 1927-730X |