Optimal chemotactic responses in stochastic environments.
Although the "adaptive" strategy used by Escherichia coli has dominated our understanding of bacterial chemotaxis, the environmental conditions under which this strategy emerged is still poorly understood. In this work, we study the performance of various chemotactic strategies under a ran...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2017-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC5482444?pdf=render |
| _version_ | 1818384057504890880 |
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| author | Martin Godány Bhavin S Khatri Richard A Goldstein |
| author_facet | Martin Godány Bhavin S Khatri Richard A Goldstein |
| author_sort | Martin Godány |
| collection | DOAJ |
| description | Although the "adaptive" strategy used by Escherichia coli has dominated our understanding of bacterial chemotaxis, the environmental conditions under which this strategy emerged is still poorly understood. In this work, we study the performance of various chemotactic strategies under a range of stochastic time- and space-varying attractant distributions in silico. We describe a novel "speculator" response in which the bacterium compare the current attractant concentration to the long-term average; if it is higher then they tumble persistently, while if it is lower than the average, bacteria swim away in search of more favorable conditions. We demonstrate how this response explains the experimental behavior of aerobically-grown Rhodobacter sphaeroides and that under spatially complex but slowly-changing nutrient conditions the speculator response is as effective as the adaptive strategy of E. coli. |
| first_indexed | 2024-12-14T03:16:12Z |
| format | Article |
| id | doaj.art-66c28eeab21b4280abd61dd4046d0a26 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-14T03:16:12Z |
| publishDate | 2017-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-66c28eeab21b4280abd61dd4046d0a262022-12-21T23:19:07ZengPublic Library of Science (PLoS)PLoS ONE1932-62032017-01-01126e017911110.1371/journal.pone.0179111Optimal chemotactic responses in stochastic environments.Martin GodányBhavin S KhatriRichard A GoldsteinAlthough the "adaptive" strategy used by Escherichia coli has dominated our understanding of bacterial chemotaxis, the environmental conditions under which this strategy emerged is still poorly understood. In this work, we study the performance of various chemotactic strategies under a range of stochastic time- and space-varying attractant distributions in silico. We describe a novel "speculator" response in which the bacterium compare the current attractant concentration to the long-term average; if it is higher then they tumble persistently, while if it is lower than the average, bacteria swim away in search of more favorable conditions. We demonstrate how this response explains the experimental behavior of aerobically-grown Rhodobacter sphaeroides and that under spatially complex but slowly-changing nutrient conditions the speculator response is as effective as the adaptive strategy of E. coli.http://europepmc.org/articles/PMC5482444?pdf=render |
| spellingShingle | Martin Godány Bhavin S Khatri Richard A Goldstein Optimal chemotactic responses in stochastic environments. PLoS ONE |
| title | Optimal chemotactic responses in stochastic environments. |
| title_full | Optimal chemotactic responses in stochastic environments. |
| title_fullStr | Optimal chemotactic responses in stochastic environments. |
| title_full_unstemmed | Optimal chemotactic responses in stochastic environments. |
| title_short | Optimal chemotactic responses in stochastic environments. |
| title_sort | optimal chemotactic responses in stochastic environments |
| url | http://europepmc.org/articles/PMC5482444?pdf=render |
| work_keys_str_mv | AT martingodany optimalchemotacticresponsesinstochasticenvironments AT bhavinskhatri optimalchemotacticresponsesinstochasticenvironments AT richardagoldstein optimalchemotacticresponsesinstochasticenvironments |