Targeting Nuclear Receptors with Lentivirus-Delivered Small RNAs in Primary Human Hepatocytes

Background: RNA interference (RNAi) has tremendous potential for investigating gene function and for developing new therapies. Primary human hepatocytes (PHH) are the “gold standard” for studying the regulation of hepatic metabolism in vitro. However, application of RNAi in PHH has some technical hu...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Maria Thomas, Jessica K. Rieger, Benjamin A. Kandel, Kathrin Klein, Ulrich M. Zanger
التنسيق: مقال
اللغة:English
منشور في: Cell Physiol Biochem Press GmbH & Co KG 2014-07-01
سلاسل:Cellular Physiology and Biochemistry
الموضوعات:
الوصول للمادة أونلاين:http://www.karger.com/Article/FullText/362976