Analysis of biomarkers for prediction of idiopathic infertility in Large White Yorkshire boar (Sus scrofa domesticus)
The experiment was conducted to analyze biomarkers like pH, calcium (Ca2+), cholesterol (Ch), estradiol (E2) and vitamin D (Vit-D) in the serum for prediction of idiopathic infertility and its early amelioration. pH of epididymal luminal fluids (ELF) and concentrations of Ca2+, Ch, E2 and Vit-D wer...
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| Format: | Article |
| Language: | English |
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Indian Council of Agricultural Research
2020-03-01
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| Series: | Indian Journal of Animal Sciences |
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| Online Access: | https://epubs.icar.org.in/index.php/IJAnS/article/view/98770 |
| _version_ | 1797896743949434880 |
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| author | SOMRAJ CHATTARAJ SIDDHARTHA BASU KALYANI RAY SANJOY DATTA PRADIP SARKAR DURGADAS MANDAL |
| author_facet | SOMRAJ CHATTARAJ SIDDHARTHA BASU KALYANI RAY SANJOY DATTA PRADIP SARKAR DURGADAS MANDAL |
| author_sort | SOMRAJ CHATTARAJ |
| collection | DOAJ |
| description |
The experiment was conducted to analyze biomarkers like pH, calcium (Ca2+), cholesterol (Ch), estradiol (E2) and vitamin D (Vit-D) in the serum for prediction of idiopathic infertility and its early amelioration. pH of epididymal luminal fluids (ELF) and concentrations of Ca2+, Ch, E2 and Vit-D were measured in serum, as well as in epididymal luminal fluids (ELF) and sperm cytosolic fluids (SCF) from caput, corpus and cauda epididymis of healthy, mature Large Yorkshire breed of boar (n=100). The levels of these bio-molecular components in the serum, in ELF and SCF from different epididymal segments were used statistically to develop a Curve Fit Regression Equations and a prediction equation to predict the quantum of these bio-molecules in the ELF and SCF by estimating their levels in the serum which would have been very difficult otherwise to be estimated in live animals. Further, from the clinical point of view, present findings about the spermatozoa maturation can pave the way for development of specific marker(s) that will assist in the development of new arena for both the prediction and early diagnosis of male infertility and for improving treatment modalities of male infertility, since epididymal dysfunctions are related to cases of idiopathic male infertility.
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| first_indexed | 2024-04-10T07:47:37Z |
| format | Article |
| id | doaj.art-66c5983ebf284c21a849527f27deb8e1 |
| institution | Directory Open Access Journal |
| issn | 0367-8318 2394-3327 |
| language | English |
| last_indexed | 2024-04-10T07:47:37Z |
| publishDate | 2020-03-01 |
| publisher | Indian Council of Agricultural Research |
| record_format | Article |
| series | Indian Journal of Animal Sciences |
| spelling | doaj.art-66c5983ebf284c21a849527f27deb8e12023-02-23T10:27:53ZengIndian Council of Agricultural ResearchIndian Journal of Animal Sciences0367-83182394-33272020-03-0190210.56093/ijans.v90i2.98770Analysis of biomarkers for prediction of idiopathic infertility in Large White Yorkshire boar (Sus scrofa domesticus)SOMRAJ CHATTARAJ0SIDDHARTHA BASU1KALYANI RAY2SANJOY DATTA3PRADIP SARKAR4DURGADAS MANDAL5Veterinary Officer, Animal Resource Development Department, Govt. of West BengalProfessor, West Bengal University of Animal and Fishery Sciences, Belgachia, Kolkata, West Bengal 700 037 IndiaProfessor, West Bengal University of Animal and Fishery Sciences, Belgachia, Kolkata, West Bengal 700 037 IndiaAssistant Professor, Department of Animal Genetics and Breeding, WBUAFS, KolkataAssistant Professor, West Bengal University of Animal and Fishery Sciences, Belgachia, Kolkata, West Bengal 700 037 IndiaAssistant Professor, West Bengal University of Animal and Fishery Sciences, Belgachia, Kolkata, West Bengal 700 037 India The experiment was conducted to analyze biomarkers like pH, calcium (Ca2+), cholesterol (Ch), estradiol (E2) and vitamin D (Vit-D) in the serum for prediction of idiopathic infertility and its early amelioration. pH of epididymal luminal fluids (ELF) and concentrations of Ca2+, Ch, E2 and Vit-D were measured in serum, as well as in epididymal luminal fluids (ELF) and sperm cytosolic fluids (SCF) from caput, corpus and cauda epididymis of healthy, mature Large Yorkshire breed of boar (n=100). The levels of these bio-molecular components in the serum, in ELF and SCF from different epididymal segments were used statistically to develop a Curve Fit Regression Equations and a prediction equation to predict the quantum of these bio-molecules in the ELF and SCF by estimating their levels in the serum which would have been very difficult otherwise to be estimated in live animals. Further, from the clinical point of view, present findings about the spermatozoa maturation can pave the way for development of specific marker(s) that will assist in the development of new arena for both the prediction and early diagnosis of male infertility and for improving treatment modalities of male infertility, since epididymal dysfunctions are related to cases of idiopathic male infertility. https://epubs.icar.org.in/index.php/IJAnS/article/view/98770BiomoleculesCurve fit regression equationsEpididymal lumen fluid (ELF)Sperm cytosolic fluid (SCF) |
| spellingShingle | SOMRAJ CHATTARAJ SIDDHARTHA BASU KALYANI RAY SANJOY DATTA PRADIP SARKAR DURGADAS MANDAL Analysis of biomarkers for prediction of idiopathic infertility in Large White Yorkshire boar (Sus scrofa domesticus) Indian Journal of Animal Sciences Biomolecules Curve fit regression equations Epididymal lumen fluid (ELF) Sperm cytosolic fluid (SCF) |
| title | Analysis of biomarkers for prediction of idiopathic infertility in Large White Yorkshire boar (Sus scrofa domesticus) |
| title_full | Analysis of biomarkers for prediction of idiopathic infertility in Large White Yorkshire boar (Sus scrofa domesticus) |
| title_fullStr | Analysis of biomarkers for prediction of idiopathic infertility in Large White Yorkshire boar (Sus scrofa domesticus) |
| title_full_unstemmed | Analysis of biomarkers for prediction of idiopathic infertility in Large White Yorkshire boar (Sus scrofa domesticus) |
| title_short | Analysis of biomarkers for prediction of idiopathic infertility in Large White Yorkshire boar (Sus scrofa domesticus) |
| title_sort | analysis of biomarkers for prediction of idiopathic infertility in large white yorkshire boar sus scrofa domesticus |
| topic | Biomolecules Curve fit regression equations Epididymal lumen fluid (ELF) Sperm cytosolic fluid (SCF) |
| url | https://epubs.icar.org.in/index.php/IJAnS/article/view/98770 |
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