Antiradical and Antioxidant Activity of Compounds Containing 1,3-Dicarbonyl Moiety: An Overview

Free radicals and oxidants may cause various damages both to the lifeworld and different products. A typical solution for the prophylaxis of oxidation-caused conditions is the usage of various antioxidants. Among them, various classes are found—polyphenols, conjugated polyalkenes, and some sulfur an...

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Main Authors: Laima Bērziņa, Inese Mieriņa
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/28/17/6203
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author Laima Bērziņa
Inese Mieriņa
author_facet Laima Bērziņa
Inese Mieriņa
author_sort Laima Bērziņa
collection DOAJ
description Free radicals and oxidants may cause various damages both to the lifeworld and different products. A typical solution for the prophylaxis of oxidation-caused conditions is the usage of various antioxidants. Among them, various classes are found—polyphenols, conjugated polyalkenes, and some sulfur and nitrogen derivatives. Regarding the active site in the molecules, a widely discussed group of compounds are 1,3-dicarbonyl compounds. Among them are natural (e.g., curcumin and pulvinic acids) and synthetic (e.g., 4-hydroxy coumarins, substituted Meldrum’s acids) compounds. Herein, information about various compounds containing the 1,3-dicarbonyl moiety is covered, and their antiradical and antioxidant activity, depending on the structure, is discussed.
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spelling doaj.art-66c5e5fe1956418bad5b5ca6daf595252023-11-19T08:32:44ZengMDPI AGMolecules1420-30492023-08-012817620310.3390/molecules28176203Antiradical and Antioxidant Activity of Compounds Containing 1,3-Dicarbonyl Moiety: An OverviewLaima Bērziņa0Inese Mieriņa1Institute of Technology of Organic Chemistry, Faculty of Materials Science and Applied Chemistry, Riga Technical University, LV-1048 Riga, LatviaInstitute of Technology of Organic Chemistry, Faculty of Materials Science and Applied Chemistry, Riga Technical University, LV-1048 Riga, LatviaFree radicals and oxidants may cause various damages both to the lifeworld and different products. A typical solution for the prophylaxis of oxidation-caused conditions is the usage of various antioxidants. Among them, various classes are found—polyphenols, conjugated polyalkenes, and some sulfur and nitrogen derivatives. Regarding the active site in the molecules, a widely discussed group of compounds are 1,3-dicarbonyl compounds. Among them are natural (e.g., curcumin and pulvinic acids) and synthetic (e.g., 4-hydroxy coumarins, substituted Meldrum’s acids) compounds. Herein, information about various compounds containing the 1,3-dicarbonyl moiety is covered, and their antiradical and antioxidant activity, depending on the structure, is discussed.https://www.mdpi.com/1420-3049/28/17/6203antiradical activityantioxidant activity1,3-dicarbonyl compoundβ-dicarbonyl compound1,3-diketoneketo–enol tautomerism
spellingShingle Laima Bērziņa
Inese Mieriņa
Antiradical and Antioxidant Activity of Compounds Containing 1,3-Dicarbonyl Moiety: An Overview
Molecules
antiradical activity
antioxidant activity
1,3-dicarbonyl compound
β-dicarbonyl compound
1,3-diketone
keto–enol tautomerism
title Antiradical and Antioxidant Activity of Compounds Containing 1,3-Dicarbonyl Moiety: An Overview
title_full Antiradical and Antioxidant Activity of Compounds Containing 1,3-Dicarbonyl Moiety: An Overview
title_fullStr Antiradical and Antioxidant Activity of Compounds Containing 1,3-Dicarbonyl Moiety: An Overview
title_full_unstemmed Antiradical and Antioxidant Activity of Compounds Containing 1,3-Dicarbonyl Moiety: An Overview
title_short Antiradical and Antioxidant Activity of Compounds Containing 1,3-Dicarbonyl Moiety: An Overview
title_sort antiradical and antioxidant activity of compounds containing 1 3 dicarbonyl moiety an overview
topic antiradical activity
antioxidant activity
1,3-dicarbonyl compound
β-dicarbonyl compound
1,3-diketone
keto–enol tautomerism
url https://www.mdpi.com/1420-3049/28/17/6203
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