Epidemiology of Psoriasis and Comorbid Diseases: A Narrative Review
Psoriasis is a chronic autoimmune inflammatory disease that remains active for a long period, even for life in most patients. The impact of psoriasis on health is not only limited to the skin, but also influences multiple systems of the body, even mental health. With the increasing of literature on...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-06-01
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| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2022.880201/full |
| _version_ | 1818164136150827008 |
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| author | Jin Bu Ruilian Ding Liangjia Zhou Xiangming Chen Erxia Shen Erxia Shen |
| author_facet | Jin Bu Ruilian Ding Liangjia Zhou Xiangming Chen Erxia Shen Erxia Shen |
| author_sort | Jin Bu |
| collection | DOAJ |
| description | Psoriasis is a chronic autoimmune inflammatory disease that remains active for a long period, even for life in most patients. The impact of psoriasis on health is not only limited to the skin, but also influences multiple systems of the body, even mental health. With the increasing of literature on the association between psoriasis and extracutaneous systems, a better understanding of psoriasis as an autoimmune disease with systemic inflammation is created. Except for cardiometabolic diseases, gastrointestinal diseases, chronic kidney diseases, malignancy, and infections that have received much attention, the association between psoriasis and more systemic diseases, including the skin system, reproductive system, and oral and ocular systems has also been revealed, and mental health diseases draw more attention not just because of the negative mental and mood influence caused by skin lesions, but a common immune-inflammatory mechanism identified of the two systemic diseases. This review summarizes the epidemiological evidence supporting the association between psoriasis and important and/or newly reported systemic diseases in the past 5 years, and may help to comprehensively recognize the comorbidity burden related to psoriasis, further to improve the management of people with psoriasis. |
| first_indexed | 2024-12-11T17:00:39Z |
| format | Article |
| id | doaj.art-66c685049b7b45c09cd4192b838e387e |
| institution | Directory Open Access Journal |
| issn | 1664-3224 |
| language | English |
| last_indexed | 2024-12-11T17:00:39Z |
| publishDate | 2022-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj.art-66c685049b7b45c09cd4192b838e387e2022-12-22T00:57:49ZengFrontiers Media S.A.Frontiers in Immunology1664-32242022-06-011310.3389/fimmu.2022.880201880201Epidemiology of Psoriasis and Comorbid Diseases: A Narrative ReviewJin Bu0Ruilian Ding1Liangjia Zhou2Xiangming Chen3Erxia Shen4Erxia Shen5Hospital for Skin Disease (Institute of Dermatology), Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, ChinaHospital for Skin Disease (Institute of Dermatology), Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, ChinaHospital for Skin Disease (Institute of Dermatology), Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, ChinaSino-French Hoffmann Institute, School of Basic Medicine, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, ChinaSino-French Hoffmann Institute, School of Basic Medicine, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, ChinaThe State Key Laboratory of Respiratory Disease, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, ChinaPsoriasis is a chronic autoimmune inflammatory disease that remains active for a long period, even for life in most patients. The impact of psoriasis on health is not only limited to the skin, but also influences multiple systems of the body, even mental health. With the increasing of literature on the association between psoriasis and extracutaneous systems, a better understanding of psoriasis as an autoimmune disease with systemic inflammation is created. Except for cardiometabolic diseases, gastrointestinal diseases, chronic kidney diseases, malignancy, and infections that have received much attention, the association between psoriasis and more systemic diseases, including the skin system, reproductive system, and oral and ocular systems has also been revealed, and mental health diseases draw more attention not just because of the negative mental and mood influence caused by skin lesions, but a common immune-inflammatory mechanism identified of the two systemic diseases. This review summarizes the epidemiological evidence supporting the association between psoriasis and important and/or newly reported systemic diseases in the past 5 years, and may help to comprehensively recognize the comorbidity burden related to psoriasis, further to improve the management of people with psoriasis.https://www.frontiersin.org/articles/10.3389/fimmu.2022.880201/fullpsoriasis diseasecomorbid diseaseepidemiologyautoimmune chronic diseasesprevalence |
| spellingShingle | Jin Bu Ruilian Ding Liangjia Zhou Xiangming Chen Erxia Shen Erxia Shen Epidemiology of Psoriasis and Comorbid Diseases: A Narrative Review Frontiers in Immunology psoriasis disease comorbid disease epidemiology autoimmune chronic diseases prevalence |
| title | Epidemiology of Psoriasis and Comorbid Diseases: A Narrative Review |
| title_full | Epidemiology of Psoriasis and Comorbid Diseases: A Narrative Review |
| title_fullStr | Epidemiology of Psoriasis and Comorbid Diseases: A Narrative Review |
| title_full_unstemmed | Epidemiology of Psoriasis and Comorbid Diseases: A Narrative Review |
| title_short | Epidemiology of Psoriasis and Comorbid Diseases: A Narrative Review |
| title_sort | epidemiology of psoriasis and comorbid diseases a narrative review |
| topic | psoriasis disease comorbid disease epidemiology autoimmune chronic diseases prevalence |
| url | https://www.frontiersin.org/articles/10.3389/fimmu.2022.880201/full |
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