Brazilian Flavivirus phylogeny based on NS5
In this work, a comprehensive phylogenetic study based on 600 base pair nucleotide and on putative 200 amino acid sequences of NS5 was carried out in order to establish genetic relationships among 15 strains of 10 Brazilian flaviviruses: Bussuquara, Cacipacore, dengue type 1, 2 and 4, Iguape, Ilheus...
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| Format: | Article |
| Language: | English |
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Fundação Oswaldo Cruz (FIOCRUZ)
2003-04-01
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| Series: | Memorias do Instituto Oswaldo Cruz |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762003000300015 |
| _version_ | 1797757042214043648 |
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| author | Flávia Graciela Baleotti Marcos Lázaro Moreli Luiz Tadeu Moraes Figueiredo |
| author_facet | Flávia Graciela Baleotti Marcos Lázaro Moreli Luiz Tadeu Moraes Figueiredo |
| author_sort | Flávia Graciela Baleotti |
| collection | DOAJ |
| description | In this work, a comprehensive phylogenetic study based on 600 base pair nucleotide and on putative 200 amino acid sequences of NS5 was carried out in order to establish genetic relationships among 15 strains of 10 Brazilian flaviviruses: Bussuquara, Cacipacore, dengue type 1, 2 and 4, Iguape, Ilheus, Rocio, Saint Louis encephalitis (SLE), and yellow fever. Phylogenetic trees were created by neighbor-joining and maximum parsimony methods. These trees showed Brazilian flaviviruses grouped into three main branches: yellow fever branch, dengue branch subdivided in types 1, 2 and 4 branches, and Japanese encephalitis virus (JEV) complex branch including SLE virus strains, Cacipacore, Iguape, Rocio, Ilheus and Bussuquara. Viruses transmitted by Aedes mosquitoes, such as dengue and urban yellow fever, that are also the only Flavivirus causing hemorrhagic fevers in Brazil, were grouped in the same cluster. Encephalitis associated viruses, transmitted by Culex mosquitoes such as JEV complex branch including SLE virus strains, Cacipacore, Iguape, Rocio, Ilheus and Bussuquara were also grouped in the same clade. |
| first_indexed | 2024-03-12T18:10:19Z |
| format | Article |
| id | doaj.art-66c83664c8af4f149b9c00cf5a048d44 |
| institution | Directory Open Access Journal |
| issn | 0074-0276 1678-8060 |
| language | English |
| last_indexed | 2024-03-12T18:10:19Z |
| publishDate | 2003-04-01 |
| publisher | Fundação Oswaldo Cruz (FIOCRUZ) |
| record_format | Article |
| series | Memorias do Instituto Oswaldo Cruz |
| spelling | doaj.art-66c83664c8af4f149b9c00cf5a048d442023-08-02T09:16:22ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz0074-02761678-80602003-04-0198337938210.1590/S0074-02762003000300015Brazilian Flavivirus phylogeny based on NS5Flávia Graciela BaleottiMarcos Lázaro MoreliLuiz Tadeu Moraes FigueiredoIn this work, a comprehensive phylogenetic study based on 600 base pair nucleotide and on putative 200 amino acid sequences of NS5 was carried out in order to establish genetic relationships among 15 strains of 10 Brazilian flaviviruses: Bussuquara, Cacipacore, dengue type 1, 2 and 4, Iguape, Ilheus, Rocio, Saint Louis encephalitis (SLE), and yellow fever. Phylogenetic trees were created by neighbor-joining and maximum parsimony methods. These trees showed Brazilian flaviviruses grouped into three main branches: yellow fever branch, dengue branch subdivided in types 1, 2 and 4 branches, and Japanese encephalitis virus (JEV) complex branch including SLE virus strains, Cacipacore, Iguape, Rocio, Ilheus and Bussuquara. Viruses transmitted by Aedes mosquitoes, such as dengue and urban yellow fever, that are also the only Flavivirus causing hemorrhagic fevers in Brazil, were grouped in the same cluster. Encephalitis associated viruses, transmitted by Culex mosquitoes such as JEV complex branch including SLE virus strains, Cacipacore, Iguape, Rocio, Ilheus and Bussuquara were also grouped in the same clade.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762003000300015Brazilian FlavivirusNS5 proteinFlavivirus phylogenyBrazil |
| spellingShingle | Flávia Graciela Baleotti Marcos Lázaro Moreli Luiz Tadeu Moraes Figueiredo Brazilian Flavivirus phylogeny based on NS5 Memorias do Instituto Oswaldo Cruz Brazilian Flavivirus NS5 protein Flavivirus phylogeny Brazil |
| title | Brazilian Flavivirus phylogeny based on NS5 |
| title_full | Brazilian Flavivirus phylogeny based on NS5 |
| title_fullStr | Brazilian Flavivirus phylogeny based on NS5 |
| title_full_unstemmed | Brazilian Flavivirus phylogeny based on NS5 |
| title_short | Brazilian Flavivirus phylogeny based on NS5 |
| title_sort | brazilian flavivirus phylogeny based on ns5 |
| topic | Brazilian Flavivirus NS5 protein Flavivirus phylogeny Brazil |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762003000300015 |
| work_keys_str_mv | AT flaviagracielabaleotti brazilianflavivirusphylogenybasedonns5 AT marcoslazaromoreli brazilianflavivirusphylogenybasedonns5 AT luiztadeumoraesfigueiredo brazilianflavivirusphylogenybasedonns5 |