Development of Zeise’s Salt Derivatives Bearing Substituted Acetylsalicylic Acid Substructures as Cytotoxic COX Inhibitors

Development of Zeise’s Salt Derivatives Bearing Substituted Acetylsalicylic Acid Substructures as Cytotoxic COX Inhibitors

Zeise’s salt derivatives of the potassium trichlorido[η<sup>2</sup>-((prop-2-en/but-3-en)-1-yl)-2-acetoxybenzoate]platinate(II) type (ASA-Prop-PtCl<sub>3</sub>/ASA-But-PtCl<sub>3</sub> derivatives) were synthesized and characterized regarding their structure, stab...

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Bibliographic Details
Main Authors: Alexander Weninger, Jessica Sagasser, Victoria Obermoser, Josef Egger, Susanna Wisboeck, Qianqian Qiu, Miriam Ladstaetter, Andrea Cucchiaro, Klaus Wurst, Daniel Baecker, Ronald Gust
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Pharmaceutics
Subjects:
anticancer
antiproliferative activity
capillary electrophoresis
chlorination
COX-inhibition
cyclooxygenase enzyme
Online Access:https://www.mdpi.com/1999-4923/15/6/1573

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https://www.mdpi.com/1999-4923/15/6/1573

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