PRACTICAL ASPECTS OF APIXABAN USE IN CLINICAL PRACTICE: VIEW POINT OF CLINICAL PHARMACOLOGIST

<p>Apixaban is a "new" oral anticoagulant, direct Xa factor inhibitor with a good evidence base of the efficacy in the prevention of ischemic stroke in patients with atrial fibrillation. The article is devoted to apixaban use in clinical practice: examination before apixaban administ...

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Main Authors: D. A. Sychev, I. I. Sinitsina, G. Yu. Zakharova, M. I. Savel'eva, A. V. Ryabova, A. V. Kryukov, A. Yu. Yurovskii
Format: Article
Language:English
Published: Столичная издательская компания 2015-09-01
Series:Рациональная фармакотерапия в кардиологии
Subjects:
Online Access:http://www.rpcardio.ru/jour/article/view/154
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author D. A. Sychev
I. I. Sinitsina
G. Yu. Zakharova
M. I. Savel'eva
A. V. Ryabova
A. V. Kryukov
A. Yu. Yurovskii
author_facet D. A. Sychev
I. I. Sinitsina
G. Yu. Zakharova
M. I. Savel'eva
A. V. Ryabova
A. V. Kryukov
A. Yu. Yurovskii
author_sort D. A. Sychev
collection DOAJ
description <p>Apixaban is a "new" oral anticoagulant, direct Xa factor inhibitor with a good evidence base of the efficacy in the prevention of ischemic stroke in patients with atrial fibrillation. The article is devoted to apixaban use in clinical practice: examination before apixaban administration, clinical situation when laboratory control and monitoring are needed, drugs interactions (at the level of CYP3A4, P-gp), management of patients with bleeding because of apixaban therapy (including antidotes application), perioperative management of patients receiving apixaban.</p>
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spelling doaj.art-66ccb771d501455f8b3489d168248d672023-08-02T04:30:37ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532015-09-0111220921610.1234/1819-6446-2015-2-209-216154PRACTICAL ASPECTS OF APIXABAN USE IN CLINICAL PRACTICE: VIEW POINT OF CLINICAL PHARMACOLOGISTD. A. Sychev0I. I. Sinitsina1G. Yu. Zakharova2M. I. Savel'eva3A. V. Ryabova4A. V. Kryukov5A. Yu. Yurovskii6Российская медицинская академия последипломного образованияРоссийская медицинская академия последипломного образованияРоссийская медицинская академия последипломного образованияРоссийская медицинская академия последипломного образованияРоссийская медицинская академия последипломного образованияРоссийская медицинская академия последипломного образованияРоссийская медицинская академия последипломного образования<p>Apixaban is a "new" oral anticoagulant, direct Xa factor inhibitor with a good evidence base of the efficacy in the prevention of ischemic stroke in patients with atrial fibrillation. The article is devoted to apixaban use in clinical practice: examination before apixaban administration, clinical situation when laboratory control and monitoring are needed, drugs interactions (at the level of CYP3A4, P-gp), management of patients with bleeding because of apixaban therapy (including antidotes application), perioperative management of patients receiving apixaban.</p>http://www.rpcardio.ru/jour/article/view/154новые пероральные антикоагулянтыапиксабанклиническая фармакологиямежлекарственное взаимодействиекровотеченияпериоперацион-ное ведение
spellingShingle D. A. Sychev
I. I. Sinitsina
G. Yu. Zakharova
M. I. Savel'eva
A. V. Ryabova
A. V. Kryukov
A. Yu. Yurovskii
PRACTICAL ASPECTS OF APIXABAN USE IN CLINICAL PRACTICE: VIEW POINT OF CLINICAL PHARMACOLOGIST
Рациональная фармакотерапия в кардиологии
новые пероральные антикоагулянты
апиксабан
клиническая фармакология
межлекарственное взаимодействие
кровотечения
периоперацион-ное ведение
title PRACTICAL ASPECTS OF APIXABAN USE IN CLINICAL PRACTICE: VIEW POINT OF CLINICAL PHARMACOLOGIST
title_full PRACTICAL ASPECTS OF APIXABAN USE IN CLINICAL PRACTICE: VIEW POINT OF CLINICAL PHARMACOLOGIST
title_fullStr PRACTICAL ASPECTS OF APIXABAN USE IN CLINICAL PRACTICE: VIEW POINT OF CLINICAL PHARMACOLOGIST
title_full_unstemmed PRACTICAL ASPECTS OF APIXABAN USE IN CLINICAL PRACTICE: VIEW POINT OF CLINICAL PHARMACOLOGIST
title_short PRACTICAL ASPECTS OF APIXABAN USE IN CLINICAL PRACTICE: VIEW POINT OF CLINICAL PHARMACOLOGIST
title_sort practical aspects of apixaban use in clinical practice view point of clinical pharmacologist
topic новые пероральные антикоагулянты
апиксабан
клиническая фармакология
межлекарственное взаимодействие
кровотечения
периоперацион-ное ведение
url http://www.rpcardio.ru/jour/article/view/154
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AT avryabova practicalaspectsofapixabanuseinclinicalpracticeviewpointofclinicalpharmacologist
AT avkryukov practicalaspectsofapixabanuseinclinicalpracticeviewpointofclinicalpharmacologist
AT ayuyurovskii practicalaspectsofapixabanuseinclinicalpracticeviewpointofclinicalpharmacologist