Simultaneous Measurement of Tricarboxylic Acid Cycle Intermediates in Different Biological Matrices Using Liquid Chromatography–Tandem Mass Spectrometry; Quantitation and Comparison of TCA Cycle Intermediates in Human Serum, Plasma, Kasumi-1 Cell and Murine Liver Tissue
The tricarboxylic acid (TCA) cycle is a central part of carbon and energy metabolism, also connecting to glycolysis, amino acid, and lipid metabolism. The quantitation of the TCA cycle intermediate within one method is lucrative due to the interest in central carbon metabolism profiling in cells and...
Main Authors: | Ramji Rathod, Bharat Gajera, Kenneth Nazir, Janne Wallenius, Vidya Velagapudi |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-03-01
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Series: | Metabolites |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-1989/10/3/103 |
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