Hidradenitis Suppurativa: The Influence of Gender, the Importance of Trigger Factors and the Implications for Patient Habits

Hidradenitis suppurativa (HS) is a debilitating, chronic, inflammatory skin disease primarily affecting apocrine gland-rich areas of the body. On the one hand, the presence of triggering factors—some identified, others only hypothesized—may initiate or perpetuate the pathogenic process of HS. In add...

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Main Authors: Elia Rosi, Maria Thais Fastame, Gianmarco Silvi, Prisca Guerra, Giulia Nunziati, Antonella Di Cesare, Ilaria Scandagli, Federica Ricceri, Francesca Prignano
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/10/11/2973
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author Elia Rosi
Maria Thais Fastame
Gianmarco Silvi
Prisca Guerra
Giulia Nunziati
Antonella Di Cesare
Ilaria Scandagli
Federica Ricceri
Francesca Prignano
author_facet Elia Rosi
Maria Thais Fastame
Gianmarco Silvi
Prisca Guerra
Giulia Nunziati
Antonella Di Cesare
Ilaria Scandagli
Federica Ricceri
Francesca Prignano
author_sort Elia Rosi
collection DOAJ
description Hidradenitis suppurativa (HS) is a debilitating, chronic, inflammatory skin disease primarily affecting apocrine gland-rich areas of the body. On the one hand, the presence of triggering factors—some identified, others only hypothesized—may initiate or perpetuate the pathogenic process of HS. In addition to cigarette smoking and diet, other trigger factors, including choice of clothing, are frequently observed in clinical practice. On the other hand, the presence of disease may influence habits of HS patients. Indeed, high incidences of sexual and sleep impairment have been reported in these patients. Consequently, alcohol and substance abuse may be a coping strategy for the emotional and psychological disease burden. Furthermore, a greater awareness of gender differences in HS may be important for dermatologists in their own clinical practice (i.e., pregnancy and breastfeeding). Consequently, in this loop interaction, comprehensive knowledge of all factors involved is crucial for the management of HS patients. Thus, the objective of this review is to (i) discuss the influence of gender on HS, (ii) summarize the most frequent triggering factors of HS and (iii) analyze the impact of HS on patient habits.
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spelling doaj.art-66cf1d2f47c943148a79f783c24de9ff2023-11-24T07:47:01ZengMDPI AGBiomedicines2227-90592022-11-011011297310.3390/biomedicines10112973Hidradenitis Suppurativa: The Influence of Gender, the Importance of Trigger Factors and the Implications for Patient HabitsElia Rosi0Maria Thais Fastame1Gianmarco Silvi2Prisca Guerra3Giulia Nunziati4Antonella Di Cesare5Ilaria Scandagli6Federica Ricceri7Francesca Prignano8Department of Health Sciences, Section of Dermatology, University of Florence, 50125 Florence, ItalyDepartment of Health Sciences, Section of Dermatology, University of Florence, 50125 Florence, ItalyDepartment of Health Sciences, Section of Dermatology, University of Florence, 50125 Florence, ItalyDepartment of Health Sciences, Section of Dermatology, University of Florence, 50125 Florence, ItalyDepartment of Health Sciences, Section of Dermatology, University of Florence, 50125 Florence, ItalyDepartment of Health Sciences, Section of Dermatology, University of Florence, 50125 Florence, ItalyDepartment of Health Sciences, Section of Dermatology, University of Florence, 50125 Florence, ItalyDepartment of Health Sciences, Section of Dermatology, University of Florence, 50125 Florence, ItalyDepartment of Health Sciences, Section of Dermatology, University of Florence, 50125 Florence, ItalyHidradenitis suppurativa (HS) is a debilitating, chronic, inflammatory skin disease primarily affecting apocrine gland-rich areas of the body. On the one hand, the presence of triggering factors—some identified, others only hypothesized—may initiate or perpetuate the pathogenic process of HS. In addition to cigarette smoking and diet, other trigger factors, including choice of clothing, are frequently observed in clinical practice. On the other hand, the presence of disease may influence habits of HS patients. Indeed, high incidences of sexual and sleep impairment have been reported in these patients. Consequently, alcohol and substance abuse may be a coping strategy for the emotional and psychological disease burden. Furthermore, a greater awareness of gender differences in HS may be important for dermatologists in their own clinical practice (i.e., pregnancy and breastfeeding). Consequently, in this loop interaction, comprehensive knowledge of all factors involved is crucial for the management of HS patients. Thus, the objective of this review is to (i) discuss the influence of gender on HS, (ii) summarize the most frequent triggering factors of HS and (iii) analyze the impact of HS on patient habits.https://www.mdpi.com/2227-9059/10/11/2973hidradenitis suppurativatrigger factorshabitsgendersmokingdiet
spellingShingle Elia Rosi
Maria Thais Fastame
Gianmarco Silvi
Prisca Guerra
Giulia Nunziati
Antonella Di Cesare
Ilaria Scandagli
Federica Ricceri
Francesca Prignano
Hidradenitis Suppurativa: The Influence of Gender, the Importance of Trigger Factors and the Implications for Patient Habits
Biomedicines
hidradenitis suppurativa
trigger factors
habits
gender
smoking
diet
title Hidradenitis Suppurativa: The Influence of Gender, the Importance of Trigger Factors and the Implications for Patient Habits
title_full Hidradenitis Suppurativa: The Influence of Gender, the Importance of Trigger Factors and the Implications for Patient Habits
title_fullStr Hidradenitis Suppurativa: The Influence of Gender, the Importance of Trigger Factors and the Implications for Patient Habits
title_full_unstemmed Hidradenitis Suppurativa: The Influence of Gender, the Importance of Trigger Factors and the Implications for Patient Habits
title_short Hidradenitis Suppurativa: The Influence of Gender, the Importance of Trigger Factors and the Implications for Patient Habits
title_sort hidradenitis suppurativa the influence of gender the importance of trigger factors and the implications for patient habits
topic hidradenitis suppurativa
trigger factors
habits
gender
smoking
diet
url https://www.mdpi.com/2227-9059/10/11/2973
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