Ru(III) Complexes with Lonidamine-Modified Ligands

Ru(III) Complexes with Lonidamine-Modified Ligands

A series of bifunctional Ru(III) complexes with lonidamine-modified ligands (lonidamine is a selective inhibitor of aerobic glycolysis in cancer cells) was described. Redox properties of Ru(III) complexes were characterized by cyclic voltammetry. An easy reduction suggested a perspective for these a...

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Bibliographic Details
Main Authors: Ilya A. Shutkov, Yulia N. Okulova, Vladimir Yu. Tyurin, Elena V. Sokolova, Denis A. Babkov, Alexander A. Spasov, Yulia A. Gracheva, Claudia Schmidt, Kirill I. Kirsanov, Alexander A. Shtil, Olga M. Redkozubova, Elena F. Shevtsova, Elena R. Milaeva, Ingo Ott, Alexey A. Nazarov
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
lonidamine
redox balance
cell death
antiproliferative activity
thioredoxin reductase
Online Access:https://www.mdpi.com/1422-0067/22/24/13468

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