On Incidence-Dependent Management Strategies against an SEIRS Epidemic: Extinction of the Epidemic Using Allee Effect
We developed a mathematical model to study the effects of non-pharmaceutical interventions (NPIs) on the dynamics of an epidemic. The level of intervention was assessed as a fraction of the population being isolated and depended on the level of incidence of the epidemic in the population. We perform...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-06-01
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| Series: | Mathematics |
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| Online Access: | https://www.mdpi.com/2227-7390/11/13/2822 |
| _version_ | 1827734849089175552 |
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| author | Tri Nguyen-Huu Pierre Auger Ali Moussaoui |
| author_facet | Tri Nguyen-Huu Pierre Auger Ali Moussaoui |
| author_sort | Tri Nguyen-Huu |
| collection | DOAJ |
| description | We developed a mathematical model to study the effects of non-pharmaceutical interventions (NPIs) on the dynamics of an epidemic. The level of intervention was assessed as a fraction of the population being isolated and depended on the level of incidence of the epidemic in the population. We performed a mathematical analysis of the model and showed that, depending on the choice of the prevalence-dependent isolation function, it is possible to create new endemic equilibria and to change the stability of the disease-free equilibrium for which the epidemic vanishes. The model was then applied to the case of the COVID-19 pandemic. Several NPI management strategies were considered. In the case of an NPI intensity increasing with the level of infection, it is possible to avoid the initial epidemic peak of great amplitude that would have occurred without intervention and to stabilize the epidemic at a chosen and sufficiently low endemic level. In the case of an NPI intensity decreasing with the level of infection, the epidemic can be driven to extinction by generating an “Allee” effect: when the incidence is below a given level, the epidemic goes extinct whereas, above it, the epidemic will still be able take hold at a lower endemic level. Simulations illustrate that appropriate NPIs could make the COVID-19 vanish relatively fast. We show that, in the context of the COVID-19 pandemic, most countries have not chosen to use the most efficient strategies. |
| first_indexed | 2024-03-11T01:35:13Z |
| format | Article |
| id | doaj.art-66d6a799cbb34762beb0e5547bd23bbb |
| institution | Directory Open Access Journal |
| issn | 2227-7390 |
| language | English |
| last_indexed | 2024-03-11T01:35:13Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Mathematics |
| spelling | doaj.art-66d6a799cbb34762beb0e5547bd23bbb2023-11-18T17:01:51ZengMDPI AGMathematics2227-73902023-06-011113282210.3390/math11132822On Incidence-Dependent Management Strategies against an SEIRS Epidemic: Extinction of the Epidemic Using Allee EffectTri Nguyen-Huu0Pierre Auger1Ali Moussaoui2UMMISCO, Institut de Recherche Pour le Développement, Sorbonne Université, F-93143 Bondy, FranceUMMISCO, Institut de Recherche Pour le Développement, Sorbonne Université, F-93143 Bondy, FranceLaboratoire d’Analyse Non Linéaire et Mathématiques Appliquées, Department of Mathematics, Faculty of Science, University of Tlemcen, Tlemcen 13000, AlgeriaWe developed a mathematical model to study the effects of non-pharmaceutical interventions (NPIs) on the dynamics of an epidemic. The level of intervention was assessed as a fraction of the population being isolated and depended on the level of incidence of the epidemic in the population. We performed a mathematical analysis of the model and showed that, depending on the choice of the prevalence-dependent isolation function, it is possible to create new endemic equilibria and to change the stability of the disease-free equilibrium for which the epidemic vanishes. The model was then applied to the case of the COVID-19 pandemic. Several NPI management strategies were considered. In the case of an NPI intensity increasing with the level of infection, it is possible to avoid the initial epidemic peak of great amplitude that would have occurred without intervention and to stabilize the epidemic at a chosen and sufficiently low endemic level. In the case of an NPI intensity decreasing with the level of infection, the epidemic can be driven to extinction by generating an “Allee” effect: when the incidence is below a given level, the epidemic goes extinct whereas, above it, the epidemic will still be able take hold at a lower endemic level. Simulations illustrate that appropriate NPIs could make the COVID-19 vanish relatively fast. We show that, in the context of the COVID-19 pandemic, most countries have not chosen to use the most efficient strategies.https://www.mdpi.com/2227-7390/11/13/2822SEIRS modelnon-pharmaceutical interventionstarget endemic levelAllee effectCOVID-19 |
| spellingShingle | Tri Nguyen-Huu Pierre Auger Ali Moussaoui On Incidence-Dependent Management Strategies against an SEIRS Epidemic: Extinction of the Epidemic Using Allee Effect Mathematics SEIRS model non-pharmaceutical interventions target endemic level Allee effect COVID-19 |
| title | On Incidence-Dependent Management Strategies against an SEIRS Epidemic: Extinction of the Epidemic Using Allee Effect |
| title_full | On Incidence-Dependent Management Strategies against an SEIRS Epidemic: Extinction of the Epidemic Using Allee Effect |
| title_fullStr | On Incidence-Dependent Management Strategies against an SEIRS Epidemic: Extinction of the Epidemic Using Allee Effect |
| title_full_unstemmed | On Incidence-Dependent Management Strategies against an SEIRS Epidemic: Extinction of the Epidemic Using Allee Effect |
| title_short | On Incidence-Dependent Management Strategies against an SEIRS Epidemic: Extinction of the Epidemic Using Allee Effect |
| title_sort | on incidence dependent management strategies against an seirs epidemic extinction of the epidemic using allee effect |
| topic | SEIRS model non-pharmaceutical interventions target endemic level Allee effect COVID-19 |
| url | https://www.mdpi.com/2227-7390/11/13/2822 |
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