Prevalence of dementia and subtypes in Valladolid, northwestern Spain: the DEMINVALL study.
OBJECTIVE:To describe the prevalence of dementia and subtypes in a general elderly population in northwestern Spain and to analyze the influence of socio-demographic factors. METHODS:Cross-sectional, two-phase, door-to-door, population-based study. A total of 870 individuals from a rural region and...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2013-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC3798383?pdf=render |
| _version_ | 1811325840135290880 |
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| author | Miguel Angel Tola-Arribas María Isabel Yugueros María José Garea Fernando Ortega-Valín Ana Cerón-Fernández Beatriz Fernández-Malvido Antonio San José-Gallegos Marta González-Touya Ana Botrán-Velicia Vanessa Iglesias-Rodríguez Bárbara Díaz-Gómez |
| author_facet | Miguel Angel Tola-Arribas María Isabel Yugueros María José Garea Fernando Ortega-Valín Ana Cerón-Fernández Beatriz Fernández-Malvido Antonio San José-Gallegos Marta González-Touya Ana Botrán-Velicia Vanessa Iglesias-Rodríguez Bárbara Díaz-Gómez |
| author_sort | Miguel Angel Tola-Arribas |
| collection | DOAJ |
| description | OBJECTIVE:To describe the prevalence of dementia and subtypes in a general elderly population in northwestern Spain and to analyze the influence of socio-demographic factors. METHODS:Cross-sectional, two-phase, door-to-door, population-based study. A total of 870 individuals from a rural region and 2,119 individuals from an urban region of Valladolid, Spain, were involved. The seven-minute screen neurocognitive battery was used in the screening phase. A control group was included. RESULTS:A total of 2,170 individuals aged 65 to 104 years (57% women) were assessed. There were 184 subjects diagnosed with dementia. The crude prevalence was 8.5% (95% CI: 7.3-9.7). Age- and sex-adjusted prevalence was 5.5 (95% CI: 4.5-6.5). Main subtypes of dementia were: Alzheimer's disease (AD) 77.7%, Lewy Body disease, 7.6% and vascular dementia (VD) 5.9%. Crude prevalences were 6.6% (AD), 0.6% (Lewy Body disease), and 0.5% (VD). Dementia was associated with age (OR 1.14 for 1-year increase in age), female sex (OR 1.79) and the absence of formal education (OR 2.53 compared to subjects with primary education or more). CONCLUSION:The prevalence of dementia in the study population was lower than the most recent estimates for Western Europe. There was a high proportion of AD among all dementia cases and very low prevalence of VD. Old age, female sex, and low education level were independent risk factors for dementia and AD. |
| first_indexed | 2024-04-13T14:40:35Z |
| format | Article |
| id | doaj.art-66d8971fed1d4ed98fe5034ed7518af0 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-13T14:40:35Z |
| publishDate | 2013-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-66d8971fed1d4ed98fe5034ed7518af02022-12-22T02:42:55ZengPublic Library of Science (PLoS)PLoS ONE1932-62032013-01-01810e7768810.1371/journal.pone.0077688Prevalence of dementia and subtypes in Valladolid, northwestern Spain: the DEMINVALL study.Miguel Angel Tola-ArribasMaría Isabel YuguerosMaría José GareaFernando Ortega-ValínAna Cerón-FernándezBeatriz Fernández-MalvidoAntonio San José-GallegosMarta González-TouyaAna Botrán-VeliciaVanessa Iglesias-RodríguezBárbara Díaz-GómezOBJECTIVE:To describe the prevalence of dementia and subtypes in a general elderly population in northwestern Spain and to analyze the influence of socio-demographic factors. METHODS:Cross-sectional, two-phase, door-to-door, population-based study. A total of 870 individuals from a rural region and 2,119 individuals from an urban region of Valladolid, Spain, were involved. The seven-minute screen neurocognitive battery was used in the screening phase. A control group was included. RESULTS:A total of 2,170 individuals aged 65 to 104 years (57% women) were assessed. There were 184 subjects diagnosed with dementia. The crude prevalence was 8.5% (95% CI: 7.3-9.7). Age- and sex-adjusted prevalence was 5.5 (95% CI: 4.5-6.5). Main subtypes of dementia were: Alzheimer's disease (AD) 77.7%, Lewy Body disease, 7.6% and vascular dementia (VD) 5.9%. Crude prevalences were 6.6% (AD), 0.6% (Lewy Body disease), and 0.5% (VD). Dementia was associated with age (OR 1.14 for 1-year increase in age), female sex (OR 1.79) and the absence of formal education (OR 2.53 compared to subjects with primary education or more). CONCLUSION:The prevalence of dementia in the study population was lower than the most recent estimates for Western Europe. There was a high proportion of AD among all dementia cases and very low prevalence of VD. Old age, female sex, and low education level were independent risk factors for dementia and AD.http://europepmc.org/articles/PMC3798383?pdf=render |
| spellingShingle | Miguel Angel Tola-Arribas María Isabel Yugueros María José Garea Fernando Ortega-Valín Ana Cerón-Fernández Beatriz Fernández-Malvido Antonio San José-Gallegos Marta González-Touya Ana Botrán-Velicia Vanessa Iglesias-Rodríguez Bárbara Díaz-Gómez Prevalence of dementia and subtypes in Valladolid, northwestern Spain: the DEMINVALL study. PLoS ONE |
| title | Prevalence of dementia and subtypes in Valladolid, northwestern Spain: the DEMINVALL study. |
| title_full | Prevalence of dementia and subtypes in Valladolid, northwestern Spain: the DEMINVALL study. |
| title_fullStr | Prevalence of dementia and subtypes in Valladolid, northwestern Spain: the DEMINVALL study. |
| title_full_unstemmed | Prevalence of dementia and subtypes in Valladolid, northwestern Spain: the DEMINVALL study. |
| title_short | Prevalence of dementia and subtypes in Valladolid, northwestern Spain: the DEMINVALL study. |
| title_sort | prevalence of dementia and subtypes in valladolid northwestern spain the deminvall study |
| url | http://europepmc.org/articles/PMC3798383?pdf=render |
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