Hippo Pathway in Regulating Drug Resistance of Glioblastoma

Hippo Pathway in Regulating Drug Resistance of Glioblastoma

Glioblastoma (GBM) represents the most common and malignant tumor of the Central Nervous System (CNS), affecting both children and adults. GBM is one of the deadliest tumor types and it shows a strong multidrug resistance (MDR) and an immunosuppressive microenvironment which remain a great challenge...

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Bibliographic Details
Main Authors: Giacomo Casati, Laura Giunti, Anna Lisa Iorio, Arianna Marturano, Luisa Galli, Iacopo Sardi
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
glioblastoma (GBM)
signaling pathways
tumor heterogeneity
tumor microenvironment (TME)
Hippo pathway
chemoresistance
Online Access:https://www.mdpi.com/1422-0067/22/24/13431

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