Protein phosphatases in TLR signaling

Protein phosphatases in TLR signaling

Abstract Toll-like receptors (TLRs) are critical sensors for the detection of potentially harmful microbes. They are instrumental in initiating innate and adaptive immune responses against pathogenic organisms. However, exaggerated activation of TLR receptor signaling can also be responsible for the...

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Bibliographic Details
Main Authors: Clovis H. T. Seumen, Tanja M. Grimm, Christof R. Hauck
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Cell Communication and Signaling
Subjects:
Protein serine/threonine phosphatase
Toll-like receptors
Innate immunity
Phosphorylation
Inflammation
NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells)
Online Access:https://doi.org/10.1186/s12964-021-00722-1

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