HIV-associated cardiovascular pathology
The review presents the rationale for studying cardiovascular disease in HIV-infected patients, as well as the importance of specific therapy. The embrace of this problem is due the widespread use of antiretroviral therapy in the world over the past 20 years has led to an increase in t...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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«FIRMA «SILICEA» LLC
2019-11-01
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| Series: | Российский кардиологический журнал |
| Subjects: | |
| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/3196 |
| Summary: | The review presents the rationale for studying cardiovascular disease in HIV-infected patients, as well as the importance of specific therapy. The embrace of this problem is due the widespread use of antiretroviral therapy in the world over the past 20 years has led to an increase in the life expectancy of HIV patients, while cardiovascular diseases have become a mortality and disability leader. The review presents the most frequently reported cardiovascular pathology and cardiac complications in HIV patients that occur both against the background of virus-mediated action and as a result of antiretroviral therapy. Some pathogenetic mechanisms of HIV influence on cardiomyocytes and the extracellular matrix have been demonstrated, resulting in early heart failure and pulmonary hypertension. Information is given on the role of statins in the management of HIV patients with the clinically significant atherosclerosis. |
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| ISSN: | 1560-4071 2618-7620 |