Antimicrobial Coatings for Medical Textiles via Reactive Organo-Selenium Compounds
Bleached and cationized cotton fabrics were chemically modified with reactive organoselenium compounds through the nucleophilic aromatic substitution (S<sub>N</sub>Ar) reaction, which allowed for organo-selenium attachment onto the surface of cotton fabrics via covalent bonds and, in the...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-08-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/28/17/6381 |
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| author | Ejajul Hoque Phat Tran Unique Jacobo Nicholas Bergfeld Sanjit Acharya Julia L. Shamshina Ted W. Reid Noureddine Abidi |
| author_facet | Ejajul Hoque Phat Tran Unique Jacobo Nicholas Bergfeld Sanjit Acharya Julia L. Shamshina Ted W. Reid Noureddine Abidi |
| author_sort | Ejajul Hoque |
| collection | DOAJ |
| description | Bleached and cationized cotton fabrics were chemically modified with reactive organoselenium compounds through the nucleophilic aromatic substitution (S<sub>N</sub>Ar) reaction, which allowed for organo-selenium attachment onto the surface of cotton fabrics via covalent bonds and, in the case of the cationized cotton fabric, additional ionic interactions. The resulting textiles exhibited potent bactericidal activity against <i>S. aureus</i> (99.99% reduction), although only moderate activity was observed against <i>E. coli</i>. Fabrics treated with reactive organo-selenium compounds also exhibited fungicidal activities against <i>C. albicans</i>, and much higher antifungal activity was observed when organo-selenium compounds were applied to the cationized cotton in comparison to the bleached cotton. The treatment was found to be durable against rigorous washing conditions (non-ionic detergent/100 °C). This paper is the first report on a novel approach integrating the reaction of cotton fabrics with an organo-selenium antimicrobial agent. This approach is attractive because it provides a method for imparting antimicrobial properties to cotton fabrics which does not disrupt the traditional production processes of a textile mill. |
| first_indexed | 2024-03-10T23:16:22Z |
| format | Article |
| id | doaj.art-66dc40cacc8c490ba945427cd109d961 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T23:16:22Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-66dc40cacc8c490ba945427cd109d9612023-11-19T08:35:11ZengMDPI AGMolecules1420-30492023-08-012817638110.3390/molecules28176381Antimicrobial Coatings for Medical Textiles via Reactive Organo-Selenium CompoundsEjajul Hoque0Phat Tran1Unique Jacobo2Nicholas Bergfeld3Sanjit Acharya4Julia L. Shamshina5Ted W. Reid6Noureddine Abidi7Fiber and Biopolymer Research Institute, Department of Plant and Soil Science, Texas Tech University, Lubbock, TX 79409, USADepartment of Microbiology and Immunology, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USADepartment of Microbiology and Immunology, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USAHonors College, Texas Tech University, Lubbock, TX 79409, USAFiber and Biopolymer Research Institute, Department of Plant and Soil Science, Texas Tech University, Lubbock, TX 79409, USAFiber and Biopolymer Research Institute, Department of Plant and Soil Science, Texas Tech University, Lubbock, TX 79409, USAOphthalmology and Visual Sciences, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USAFiber and Biopolymer Research Institute, Department of Plant and Soil Science, Texas Tech University, Lubbock, TX 79409, USABleached and cationized cotton fabrics were chemically modified with reactive organoselenium compounds through the nucleophilic aromatic substitution (S<sub>N</sub>Ar) reaction, which allowed for organo-selenium attachment onto the surface of cotton fabrics via covalent bonds and, in the case of the cationized cotton fabric, additional ionic interactions. The resulting textiles exhibited potent bactericidal activity against <i>S. aureus</i> (99.99% reduction), although only moderate activity was observed against <i>E. coli</i>. Fabrics treated with reactive organo-selenium compounds also exhibited fungicidal activities against <i>C. albicans</i>, and much higher antifungal activity was observed when organo-selenium compounds were applied to the cationized cotton in comparison to the bleached cotton. The treatment was found to be durable against rigorous washing conditions (non-ionic detergent/100 °C). This paper is the first report on a novel approach integrating the reaction of cotton fabrics with an organo-selenium antimicrobial agent. This approach is attractive because it provides a method for imparting antimicrobial properties to cotton fabrics which does not disrupt the traditional production processes of a textile mill.https://www.mdpi.com/1420-3049/28/17/6381reactive organo-selenium compoundsmedical textilesbactericidal activityfungicidal activitycationized cotton |
| spellingShingle | Ejajul Hoque Phat Tran Unique Jacobo Nicholas Bergfeld Sanjit Acharya Julia L. Shamshina Ted W. Reid Noureddine Abidi Antimicrobial Coatings for Medical Textiles via Reactive Organo-Selenium Compounds Molecules reactive organo-selenium compounds medical textiles bactericidal activity fungicidal activity cationized cotton |
| title | Antimicrobial Coatings for Medical Textiles via Reactive Organo-Selenium Compounds |
| title_full | Antimicrobial Coatings for Medical Textiles via Reactive Organo-Selenium Compounds |
| title_fullStr | Antimicrobial Coatings for Medical Textiles via Reactive Organo-Selenium Compounds |
| title_full_unstemmed | Antimicrobial Coatings for Medical Textiles via Reactive Organo-Selenium Compounds |
| title_short | Antimicrobial Coatings for Medical Textiles via Reactive Organo-Selenium Compounds |
| title_sort | antimicrobial coatings for medical textiles via reactive organo selenium compounds |
| topic | reactive organo-selenium compounds medical textiles bactericidal activity fungicidal activity cationized cotton |
| url | https://www.mdpi.com/1420-3049/28/17/6381 |
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