P-glycoprotein acts as an immunomodulator during neuroinflammation.

P-glycoprotein acts as an immunomodulator during neuroinflammation.

BACKGROUND:Multiple sclerosis is an inflammatory demyelinating disease of the central nervous system in which autoreactive myelin-specific T cells cause extensive tissue damage, resulting in neurological deficits. In the disease process, T cells are primed in the periphery by antigen presenting dend...

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Main Authors: Gijs Kooij, Ronald Backer, Jasper J Koning, Arie Reijerkerk, Jack van Horssen, Susanne M A van der Pol, Joost Drexhage, Alfred Schinkel, Christine D Dijkstra, Joke M M den Haan, Teunis B H Geijtenbeek, Helga E de Vries
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2785479?pdf=render

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