Impact of urethrovesical anastomotic leakage after robotic radical prostatectomy on early postoperative continence

Objective: This study aimed to assess the urethrovesical anastomotic leakage (UAL) and associated factors in patients who underwent robot-assisted radical prostatectomy (RARP) and its effect on early continence. Material and Methods: The data of 81 patients who underwent RARP between Februa...

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Main Authors: Mert Kılıç, Serdar Madendere, Arzu Baygül Eden, Fadimana Bozkurt Tekkalan, Ersin Köseoğlu, Mevlana Derya Balbay
Format: Article
Language:English
Published: Ali İhsan Taşçı 2023-02-01
Series:Yeni Üroloji Dergisi
Online Access:https://dergipark.org.tr/en/pub/yud/issue/73953/1215737
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author Mert Kılıç
Serdar Madendere
Arzu Baygül Eden
Fadimana Bozkurt Tekkalan
Ersin Köseoğlu
Mevlana Derya Balbay
author_facet Mert Kılıç
Serdar Madendere
Arzu Baygül Eden
Fadimana Bozkurt Tekkalan
Ersin Köseoğlu
Mevlana Derya Balbay
author_sort Mert Kılıç
collection DOAJ
description Objective: This study aimed to assess the urethrovesical anastomotic leakage (UAL) and associated factors in patients who underwent robot-assisted radical prostatectomy (RARP) and its effect on early continence. Material and Methods: The data of 81 patients who underwent RARP between February 2017 and June 2022 were evaluated in this retrospective analysis. On the seventh postoperative day, we performed a cystography to determine whether the patients had UAL. Uni- and multivariate analyses were done to investigate the factors that could lead to UAL. Continence rates were recorded in patients at 6-12 weeks after surgery. Results: Overall 25 patients (31%) had UAL; of them 12 (15%) were mild, eight (10%) were moderate, and five (6%) were extensive. A drain/ serum creatinine ratio >1.5 and a prostate volume >53 cm3 were determined to be significant in predicting UAL in both the uni- and multivariate analyses (p=0.017 and p=0.046, respectively). On the postoperative second or third day, of the 36 patients who had drain output greater than 100 ml, eight (22%) had a high drain/serum creatinine ratio (>1.5), seven (88%) of which had UAL. According to the early period follow-up data, incontinence was prevalent in 9 (36%) of the patients with UAL and 20 (%37) of the patients without UAL (p=0.959). Conclusion: Cystography is an effective method for detecting leakage after RARP. A large prostate volume (>53 cm3) and a high postoperative drain/serum creatinine ratio (>1.5) were found to be associated with UAL. UAL had no effect on early continence. Keywords: anastomotic leak, cystography, prostatectomy, robot-assisted, urinary incontinence
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spelling doaj.art-66de7181a3794ed0acc8d9b4227d0f4e2023-02-28T12:06:42ZengAli İhsan TaşçıYeni Üroloji Dergisi1305-24892687-19552023-02-01181707710.33719/yud.2023;18-1-1215737Impact of urethrovesical anastomotic leakage after robotic radical prostatectomy on early postoperative continenceMert Kılıçhttps://orcid.org/0000-0003-1707-3890Serdar Madenderehttps://orcid.org/0000-0001-7020-0276Arzu Baygül Edenhttps://orcid.org/0000-0003-0392-6709Fadimana Bozkurt Tekkalanhttps://orcid.org/0000-0003-1430-5043Ersin Köseoğluhttps://orcid.org/0000-0002-5189-0600Mevlana Derya Balbayhttps://orcid.org/0000-0001-9706-1587 Objective: This study aimed to assess the urethrovesical anastomotic leakage (UAL) and associated factors in patients who underwent robot-assisted radical prostatectomy (RARP) and its effect on early continence. Material and Methods: The data of 81 patients who underwent RARP between February 2017 and June 2022 were evaluated in this retrospective analysis. On the seventh postoperative day, we performed a cystography to determine whether the patients had UAL. Uni- and multivariate analyses were done to investigate the factors that could lead to UAL. Continence rates were recorded in patients at 6-12 weeks after surgery. Results: Overall 25 patients (31%) had UAL; of them 12 (15%) were mild, eight (10%) were moderate, and five (6%) were extensive. A drain/ serum creatinine ratio >1.5 and a prostate volume >53 cm3 were determined to be significant in predicting UAL in both the uni- and multivariate analyses (p=0.017 and p=0.046, respectively). On the postoperative second or third day, of the 36 patients who had drain output greater than 100 ml, eight (22%) had a high drain/serum creatinine ratio (>1.5), seven (88%) of which had UAL. According to the early period follow-up data, incontinence was prevalent in 9 (36%) of the patients with UAL and 20 (%37) of the patients without UAL (p=0.959). Conclusion: Cystography is an effective method for detecting leakage after RARP. A large prostate volume (>53 cm3) and a high postoperative drain/serum creatinine ratio (>1.5) were found to be associated with UAL. UAL had no effect on early continence. Keywords: anastomotic leak, cystography, prostatectomy, robot-assisted, urinary incontinencehttps://dergipark.org.tr/en/pub/yud/issue/73953/1215737
spellingShingle Mert Kılıç
Serdar Madendere
Arzu Baygül Eden
Fadimana Bozkurt Tekkalan
Ersin Köseoğlu
Mevlana Derya Balbay
Impact of urethrovesical anastomotic leakage after robotic radical prostatectomy on early postoperative continence
Yeni Üroloji Dergisi
title Impact of urethrovesical anastomotic leakage after robotic radical prostatectomy on early postoperative continence
title_full Impact of urethrovesical anastomotic leakage after robotic radical prostatectomy on early postoperative continence
title_fullStr Impact of urethrovesical anastomotic leakage after robotic radical prostatectomy on early postoperative continence
title_full_unstemmed Impact of urethrovesical anastomotic leakage after robotic radical prostatectomy on early postoperative continence
title_short Impact of urethrovesical anastomotic leakage after robotic radical prostatectomy on early postoperative continence
title_sort impact of urethrovesical anastomotic leakage after robotic radical prostatectomy on early postoperative continence
url https://dergipark.org.tr/en/pub/yud/issue/73953/1215737
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