Mepolizumab in allergic bronchopulmonary aspergillosis complicated by infection
Allergic bronchopulmonary aspergillosis (ABPA) is an allergic reaction caused by the fungus Aspergillus, and it is often treated with steroids or antifungal agents. However, long-term use of these medications can lead to infections and drug interactions. We present the case of a 71-year-old woman wi...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-01-01
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| Series: | Respiratory Medicine Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213007123000850 |
| _version_ | 1797770820112613376 |
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| author | Toru Hamada Tomoya Katsuta Kento Aibara Shohei Nozu Junya Nakamura Haruka Kondo Sayaka Tachibana Koji Inoue Norihiko Nakanishi Tomonori Moritaka |
| author_facet | Toru Hamada Tomoya Katsuta Kento Aibara Shohei Nozu Junya Nakamura Haruka Kondo Sayaka Tachibana Koji Inoue Norihiko Nakanishi Tomonori Moritaka |
| author_sort | Toru Hamada |
| collection | DOAJ |
| description | Allergic bronchopulmonary aspergillosis (ABPA) is an allergic reaction caused by the fungus Aspergillus, and it is often treated with steroids or antifungal agents. However, long-term use of these medications can lead to infections and drug interactions. We present the case of a 71-year-old woman with ABPA who was diagnosed with hepatitis B and active hepatitis C, and sputum analysis revealed the presence of bacteria. Oral steroids were initially administered, but the patient was switched to mepolizumab because of numerous infectious complications. The early introduction of mepolizumab is effective in patients with ABPA complicated by infectious diseases. |
| first_indexed | 2024-03-12T21:27:39Z |
| format | Article |
| id | doaj.art-66e08f9681474634b47b9485709fcf23 |
| institution | Directory Open Access Journal |
| issn | 2213-0071 |
| language | English |
| last_indexed | 2024-03-12T21:27:39Z |
| publishDate | 2023-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Respiratory Medicine Case Reports |
| spelling | doaj.art-66e08f9681474634b47b9485709fcf232023-07-28T04:25:59ZengElsevierRespiratory Medicine Case Reports2213-00712023-01-0145101890Mepolizumab in allergic bronchopulmonary aspergillosis complicated by infectionToru Hamada0Tomoya Katsuta1Kento Aibara2Shohei Nozu3Junya Nakamura4Haruka Kondo5Sayaka Tachibana6Koji Inoue7Norihiko Nakanishi8Tomonori Moritaka9Corresponding author. Seiyo Municipal Hospital, Seiyo, Ehime, 797-0029, Japan.; Respiratory Medicine, Ehime Prefectural Central Hospital, Matsuyama, Ehime, 790-0024, JapanRespiratory Medicine, Ehime Prefectural Central Hospital, Matsuyama, Ehime, 790-0024, JapanRespiratory Medicine, Ehime Prefectural Central Hospital, Matsuyama, Ehime, 790-0024, JapanRespiratory Medicine, Ehime Prefectural Central Hospital, Matsuyama, Ehime, 790-0024, JapanRespiratory Medicine, Ehime Prefectural Central Hospital, Matsuyama, Ehime, 790-0024, JapanRespiratory Medicine, Ehime Prefectural Central Hospital, Matsuyama, Ehime, 790-0024, JapanRespiratory Medicine, Ehime Prefectural Central Hospital, Matsuyama, Ehime, 790-0024, JapanRespiratory Medicine, Ehime Prefectural Central Hospital, Matsuyama, Ehime, 790-0024, JapanRespiratory Medicine, Ehime Prefectural Central Hospital, Matsuyama, Ehime, 790-0024, JapanRespiratory Medicine, Ehime Prefectural Central Hospital, Matsuyama, Ehime, 790-0024, JapanAllergic bronchopulmonary aspergillosis (ABPA) is an allergic reaction caused by the fungus Aspergillus, and it is often treated with steroids or antifungal agents. However, long-term use of these medications can lead to infections and drug interactions. We present the case of a 71-year-old woman with ABPA who was diagnosed with hepatitis B and active hepatitis C, and sputum analysis revealed the presence of bacteria. Oral steroids were initially administered, but the patient was switched to mepolizumab because of numerous infectious complications. The early introduction of mepolizumab is effective in patients with ABPA complicated by infectious diseases.http://www.sciencedirect.com/science/article/pii/S2213007123000850Allergic bronchial aspergillosisMepolizumabNumerous infectious complications |
| spellingShingle | Toru Hamada Tomoya Katsuta Kento Aibara Shohei Nozu Junya Nakamura Haruka Kondo Sayaka Tachibana Koji Inoue Norihiko Nakanishi Tomonori Moritaka Mepolizumab in allergic bronchopulmonary aspergillosis complicated by infection Respiratory Medicine Case Reports Allergic bronchial aspergillosis Mepolizumab Numerous infectious complications |
| title | Mepolizumab in allergic bronchopulmonary aspergillosis complicated by infection |
| title_full | Mepolizumab in allergic bronchopulmonary aspergillosis complicated by infection |
| title_fullStr | Mepolizumab in allergic bronchopulmonary aspergillosis complicated by infection |
| title_full_unstemmed | Mepolizumab in allergic bronchopulmonary aspergillosis complicated by infection |
| title_short | Mepolizumab in allergic bronchopulmonary aspergillosis complicated by infection |
| title_sort | mepolizumab in allergic bronchopulmonary aspergillosis complicated by infection |
| topic | Allergic bronchial aspergillosis Mepolizumab Numerous infectious complications |
| url | http://www.sciencedirect.com/science/article/pii/S2213007123000850 |
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