Development of quality control parameters for the standardization of fruit of Ficus racemosa Linn. (M)
Objective: To develop a novel Standardization technique, which can pave the way for rapid determination of different phytoconstitutents of Ficus racemosa (F. racemosa) Linn. (Moraceae). From extensive literature survey it was revealed that no reports were available on, standardization parameters of...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2013-01-01
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| Series: | Journal of Acute Disease |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2221618913601286 |
| _version_ | 1818327199013404672 |
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| author | Ramandeep Singh Ashraf Ali G. Jeyabalan Satinder Kakar Alok Semwal |
| author_facet | Ramandeep Singh Ashraf Ali G. Jeyabalan Satinder Kakar Alok Semwal |
| author_sort | Ramandeep Singh |
| collection | DOAJ |
| description | Objective: To develop a novel Standardization technique, which can pave the way for rapid determination of different phytoconstitutents of Ficus racemosa (F. racemosa) Linn. (Moraceae). From extensive literature survey it was revealed that no reports were available on, standardization parameters of fruits of F. racemosa Linn.
Methods: Phytochemical test, TLC analysis, Foreign matter, Ash values, Swelling index, Foaming index, Extractive value, Moisture content, Microbiological analysis, Crude fibre content, amino acid content, aflatoxin, toxic element analysis and analysis of pesticide residue were performed in the present investigation for the quality control of the drug.
Results: Thus it was thought worthwhile to explore this plant on the basis of it's standardization parameters. Alkaloids, steroid, flavanoids and tannins were found to be present in F. racemosa Linn. extracts. Ash value, insoluble ash value, soluble ash value, crude fibre content, crude fat, Swelling index and Foaming index were found to be 3.96%w/w, 9.29%w/w, 7.45%w/w, 16.65%, (4.39±0.14), 1 cm, 10.30%w/w. The study will provide referential information for the correct identification of the crude drug.
Conclusions: These physicochemical data and phytochemical analysis of different extracts of F. racemosa Linn. is useful for further studies for pharmacological screening. In future this study will be helpful for qualitative & quantitative analysis of phytoconstituents for isolation of newer molecule from F. racemosa Linn. |
| first_indexed | 2024-12-13T12:12:28Z |
| format | Article |
| id | doaj.art-66e1644fb8f640e9aa17b69eecb99ef6 |
| institution | Directory Open Access Journal |
| issn | 2221-6189 |
| language | English |
| last_indexed | 2024-12-13T12:12:28Z |
| publishDate | 2013-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Acute Disease |
| spelling | doaj.art-66e1644fb8f640e9aa17b69eecb99ef62022-12-21T23:46:48ZengWolters Kluwer Medknow PublicationsJournal of Acute Disease2221-61892013-01-012320721310.1016/S2221-6189(13)60128-6Development of quality control parameters for the standardization of fruit of Ficus racemosa Linn. (M)Ramandeep Singh0Ashraf Ali1G. Jeyabalan2Satinder Kakar3Alok Semwal4Department of Pharmacy, Sunrise University, Alwar, Rajasthan, IndiaDepartment of Pharmacy, Sunrise University, Alwar, Rajasthan, IndiaDepartment of Pharmacy, Sunrise University, Alwar, Rajasthan, IndiaDepartment of Pharmacy, Doon Valley Institute of Pharmacy & Medicine, Karnal (Haryana), IndiaDepartment of Pharmacy, Himachal Institute of Pharmacy, Paonta Sahib (H.P), IndiaObjective: To develop a novel Standardization technique, which can pave the way for rapid determination of different phytoconstitutents of Ficus racemosa (F. racemosa) Linn. (Moraceae). From extensive literature survey it was revealed that no reports were available on, standardization parameters of fruits of F. racemosa Linn. Methods: Phytochemical test, TLC analysis, Foreign matter, Ash values, Swelling index, Foaming index, Extractive value, Moisture content, Microbiological analysis, Crude fibre content, amino acid content, aflatoxin, toxic element analysis and analysis of pesticide residue were performed in the present investigation for the quality control of the drug. Results: Thus it was thought worthwhile to explore this plant on the basis of it's standardization parameters. Alkaloids, steroid, flavanoids and tannins were found to be present in F. racemosa Linn. extracts. Ash value, insoluble ash value, soluble ash value, crude fibre content, crude fat, Swelling index and Foaming index were found to be 3.96%w/w, 9.29%w/w, 7.45%w/w, 16.65%, (4.39±0.14), 1 cm, 10.30%w/w. The study will provide referential information for the correct identification of the crude drug. Conclusions: These physicochemical data and phytochemical analysis of different extracts of F. racemosa Linn. is useful for further studies for pharmacological screening. In future this study will be helpful for qualitative & quantitative analysis of phytoconstituents for isolation of newer molecule from F. racemosa Linn.http://www.sciencedirect.com/science/article/pii/S2221618913601286StandardizationPhytochemical analysisFicus racemosaTLC |
| spellingShingle | Ramandeep Singh Ashraf Ali G. Jeyabalan Satinder Kakar Alok Semwal Development of quality control parameters for the standardization of fruit of Ficus racemosa Linn. (M) Journal of Acute Disease Standardization Phytochemical analysis Ficus racemosa TLC |
| title | Development of quality control parameters for the standardization of fruit of Ficus racemosa Linn. (M) |
| title_full | Development of quality control parameters for the standardization of fruit of Ficus racemosa Linn. (M) |
| title_fullStr | Development of quality control parameters for the standardization of fruit of Ficus racemosa Linn. (M) |
| title_full_unstemmed | Development of quality control parameters for the standardization of fruit of Ficus racemosa Linn. (M) |
| title_short | Development of quality control parameters for the standardization of fruit of Ficus racemosa Linn. (M) |
| title_sort | development of quality control parameters for the standardization of fruit of ficus racemosa linn m |
| topic | Standardization Phytochemical analysis Ficus racemosa TLC |
| url | http://www.sciencedirect.com/science/article/pii/S2221618913601286 |
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