Prenatal Stress Impairs Postnatal Learning and Memory Development via Disturbance of the cGMP–PKG Pathway and Oxidative Phosphorylation in the Hippocampus of Rats

Prenatal Stress Impairs Postnatal Learning and Memory Development via Disturbance of the cGMP–PKG Pathway and Oxidative Phosphorylation in the Hippocampus of Rats

Clinical and animal studies have found that prenatal stress can lead to pathological changes in embryos and fetuses. However, the mechanisms through which this occurs have not been made clear. In the present study, pregnant rats were subjected to chronic psychological stress during gestational days...

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Bibliographic Details
Main Authors: Yu-jie Li, Li-ping Yang, Jun-lin Hou, Xin-min Li, Lei Chen, Jiang-hui Zhu, Qi-yang Wang, Gai Li, Pei-yuan Zhao, Xi-hong Liu, Zhan-jiang Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Molecular Neuroscience
Subjects:
prenatal stress
iTRAQ
learning and memory
oxidative phosphorylation
cGMP–PKG pathway
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2020.00158/full

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