Correlation of C-reactive proteins with chronic periodontitis
Background: Acute-phase reactant proteins are synthesized in human body in response to chronic periodontal states. C-reactive protein (CRP) is a similar protein produced in response to chronic inflammatory conditions. Aim: The aim of the study was to correlate CRP levels in chronic periodontitis whe...
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Format: | Article |
Language: | English |
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Wolters Kluwer Medknow Publications
2020-01-01
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Series: | SRM Journal of Research in Dental Sciences |
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Online Access: | http://www.srmjrds.in/article.asp?issn=0976-433X;year=2020;volume=11;issue=3;spage=117;epage=122;aulast=Chatterjee |
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author | Shailja Chatterjee |
author_facet | Shailja Chatterjee |
author_sort | Shailja Chatterjee |
collection | DOAJ |
description | Background: Acute-phase reactant proteins are synthesized in human body in response to chronic periodontal states. C-reactive protein (CRP) is a similar protein produced in response to chronic inflammatory conditions. Aim: The aim of the study was to correlate CRP levels in chronic periodontitis when compared to normal controls. Materials and Methods: A total of 45 individuals suffering from chronic periodontitis and an equal numbers of controls were included in the study. Blood samples were drawn from all individuals after obtaining informed consent, and CRP levels were estimated using an ELISA kit. Unpaired t-test was performed for statistical analysis. Results: The mean CRP levels were found to be higher in periodontitis individuals as compared to normal controls. However, no statistical significance was observed on comparing both the groups. Conclusion: An elevated CRP level was obtained in the diseased group, confirming the inflammatory background response to periodontal diseases. |
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institution | Directory Open Access Journal |
issn | 2772-5243 2772-5251 |
language | English |
last_indexed | 2024-04-12T00:59:03Z |
publishDate | 2020-01-01 |
publisher | Wolters Kluwer Medknow Publications |
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series | SRM Journal of Research in Dental Sciences |
spelling | doaj.art-66e31aa0467f4a0cb8e221bd33e9848c2022-12-22T03:54:32ZengWolters Kluwer Medknow PublicationsSRM Journal of Research in Dental Sciences2772-52432772-52512020-01-0111311712210.4103/srmjrds.srmjrds_17_20Correlation of C-reactive proteins with chronic periodontitisShailja ChatterjeeBackground: Acute-phase reactant proteins are synthesized in human body in response to chronic periodontal states. C-reactive protein (CRP) is a similar protein produced in response to chronic inflammatory conditions. Aim: The aim of the study was to correlate CRP levels in chronic periodontitis when compared to normal controls. Materials and Methods: A total of 45 individuals suffering from chronic periodontitis and an equal numbers of controls were included in the study. Blood samples were drawn from all individuals after obtaining informed consent, and CRP levels were estimated using an ELISA kit. Unpaired t-test was performed for statistical analysis. Results: The mean CRP levels were found to be higher in periodontitis individuals as compared to normal controls. However, no statistical significance was observed on comparing both the groups. Conclusion: An elevated CRP level was obtained in the diseased group, confirming the inflammatory background response to periodontal diseases.http://www.srmjrds.in/article.asp?issn=0976-433X;year=2020;volume=11;issue=3;spage=117;epage=122;aulast=Chatterjeec-reactive proteinperiodontitisserum |
spellingShingle | Shailja Chatterjee Correlation of C-reactive proteins with chronic periodontitis SRM Journal of Research in Dental Sciences c-reactive protein periodontitis serum |
title | Correlation of C-reactive proteins with chronic periodontitis |
title_full | Correlation of C-reactive proteins with chronic periodontitis |
title_fullStr | Correlation of C-reactive proteins with chronic periodontitis |
title_full_unstemmed | Correlation of C-reactive proteins with chronic periodontitis |
title_short | Correlation of C-reactive proteins with chronic periodontitis |
title_sort | correlation of c reactive proteins with chronic periodontitis |
topic | c-reactive protein periodontitis serum |
url | http://www.srmjrds.in/article.asp?issn=0976-433X;year=2020;volume=11;issue=3;spage=117;epage=122;aulast=Chatterjee |
work_keys_str_mv | AT shailjachatterjee correlationofcreactiveproteinswithchronicperiodontitis |