Correlation of C-reactive proteins with chronic periodontitis

Background: Acute-phase reactant proteins are synthesized in human body in response to chronic periodontal states. C-reactive protein (CRP) is a similar protein produced in response to chronic inflammatory conditions. Aim: The aim of the study was to correlate CRP levels in chronic periodontitis whe...

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Main Author: Shailja Chatterjee
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:SRM Journal of Research in Dental Sciences
Subjects:
Online Access:http://www.srmjrds.in/article.asp?issn=0976-433X;year=2020;volume=11;issue=3;spage=117;epage=122;aulast=Chatterjee
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author Shailja Chatterjee
author_facet Shailja Chatterjee
author_sort Shailja Chatterjee
collection DOAJ
description Background: Acute-phase reactant proteins are synthesized in human body in response to chronic periodontal states. C-reactive protein (CRP) is a similar protein produced in response to chronic inflammatory conditions. Aim: The aim of the study was to correlate CRP levels in chronic periodontitis when compared to normal controls. Materials and Methods: A total of 45 individuals suffering from chronic periodontitis and an equal numbers of controls were included in the study. Blood samples were drawn from all individuals after obtaining informed consent, and CRP levels were estimated using an ELISA kit. Unpaired t-test was performed for statistical analysis. Results: The mean CRP levels were found to be higher in periodontitis individuals as compared to normal controls. However, no statistical significance was observed on comparing both the groups. Conclusion: An elevated CRP level was obtained in the diseased group, confirming the inflammatory background response to periodontal diseases.
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spelling doaj.art-66e31aa0467f4a0cb8e221bd33e9848c2022-12-22T03:54:32ZengWolters Kluwer Medknow PublicationsSRM Journal of Research in Dental Sciences2772-52432772-52512020-01-0111311712210.4103/srmjrds.srmjrds_17_20Correlation of C-reactive proteins with chronic periodontitisShailja ChatterjeeBackground: Acute-phase reactant proteins are synthesized in human body in response to chronic periodontal states. C-reactive protein (CRP) is a similar protein produced in response to chronic inflammatory conditions. Aim: The aim of the study was to correlate CRP levels in chronic periodontitis when compared to normal controls. Materials and Methods: A total of 45 individuals suffering from chronic periodontitis and an equal numbers of controls were included in the study. Blood samples were drawn from all individuals after obtaining informed consent, and CRP levels were estimated using an ELISA kit. Unpaired t-test was performed for statistical analysis. Results: The mean CRP levels were found to be higher in periodontitis individuals as compared to normal controls. However, no statistical significance was observed on comparing both the groups. Conclusion: An elevated CRP level was obtained in the diseased group, confirming the inflammatory background response to periodontal diseases.http://www.srmjrds.in/article.asp?issn=0976-433X;year=2020;volume=11;issue=3;spage=117;epage=122;aulast=Chatterjeec-reactive proteinperiodontitisserum
spellingShingle Shailja Chatterjee
Correlation of C-reactive proteins with chronic periodontitis
SRM Journal of Research in Dental Sciences
c-reactive protein
periodontitis
serum
title Correlation of C-reactive proteins with chronic periodontitis
title_full Correlation of C-reactive proteins with chronic periodontitis
title_fullStr Correlation of C-reactive proteins with chronic periodontitis
title_full_unstemmed Correlation of C-reactive proteins with chronic periodontitis
title_short Correlation of C-reactive proteins with chronic periodontitis
title_sort correlation of c reactive proteins with chronic periodontitis
topic c-reactive protein
periodontitis
serum
url http://www.srmjrds.in/article.asp?issn=0976-433X;year=2020;volume=11;issue=3;spage=117;epage=122;aulast=Chatterjee
work_keys_str_mv AT shailjachatterjee correlationofcreactiveproteinswithchronicperiodontitis