Long-Term Follow-Up of Classical Hodgkin Lymphoma and Diffuse Large B-Cell Lymphoma Survivors: Aims and Methodological Approach for Fondazione Italiana Linfomi Systematic Reviews
Advances in diagnosis and treatment of hematological malignancies has boosted attention on optimal follow-up care of survivors after cancer. To collect evidence that could inform the development of an optimal model for Italian hematology centers and the scientific community, Fondazione Italiana Linf...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-06-01
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| Series: | Cancers |
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| Online Access: | https://www.mdpi.com/2072-6694/13/12/2976 |
| _version_ | 1797530185492332544 |
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| author | Chiara Gerardi Eleonora Allocati Carla Minoia Attilio Guarini Rita Banzi |
| author_facet | Chiara Gerardi Eleonora Allocati Carla Minoia Attilio Guarini Rita Banzi |
| author_sort | Chiara Gerardi |
| collection | DOAJ |
| description | Advances in diagnosis and treatment of hematological malignancies has boosted attention on optimal follow-up care of survivors after cancer. To collect evidence that could inform the development of an optimal model for Italian hematology centers and the scientific community, Fondazione Italiana Linfomi (FIL) commissioned an analysis of the international follow-up approaches for long-term survivors after classical Hodgkin lymphoma (cHL) or diffuse large B-cell lymphoma (DLBCL). FIL set up multidisciplinary teams, representing all different skills relevant for cancer survivors. They conducted a series of systematic reviews focused on three main aspects: incidence of long-term toxicity; comparison of old or standard therapies and more recent ones; and evidence on specific follow-up approaches. The teams applied this framework to cardiological, endocrine-metabolic, neurological/cognitive, and psychological disorders, secondary cancers, fertility preservation, and lifestyles. Each team conducted comprehensive literature searches on PubMed, Embase and Cochrane Library databases up to 2020. Screening followed the PRISMA statement for reporting systematic reviews. The reviews report the results of this wide project covering the main areas of late toxicity and conditions in the long-term survival of cHL and DLBCL patients and their follow-up. From a clinical point of view, the series confirmed that the evidence on follow-up tended to focus on solid tumors with scant evidence on hematological malignancies. |
| first_indexed | 2024-03-10T10:25:24Z |
| format | Article |
| id | doaj.art-66e4fb2de5314c08a6d64b1864320bcf |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-10T10:25:24Z |
| publishDate | 2021-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-66e4fb2de5314c08a6d64b1864320bcf2023-11-22T00:04:16ZengMDPI AGCancers2072-66942021-06-011312297610.3390/cancers13122976Long-Term Follow-Up of Classical Hodgkin Lymphoma and Diffuse Large B-Cell Lymphoma Survivors: Aims and Methodological Approach for Fondazione Italiana Linfomi Systematic ReviewsChiara Gerardi0Eleonora Allocati1Carla Minoia2Attilio Guarini3Rita Banzi4Istituto di Ricerche Farmacologiche “Mario Negri” IRCCS, 20156 Milano, ItalyIstituto di Ricerche Farmacologiche “Mario Negri” IRCCS, 20156 Milano, ItalyHematology Unit-IRCCS Istituto Tumori “Giovanni Paolo II”, 70124 Bari, ItalyHematology Unit-IRCCS Istituto Tumori “Giovanni Paolo II”, 70124 Bari, ItalyIstituto di Ricerche Farmacologiche “Mario Negri” IRCCS, 20156 Milano, ItalyAdvances in diagnosis and treatment of hematological malignancies has boosted attention on optimal follow-up care of survivors after cancer. To collect evidence that could inform the development of an optimal model for Italian hematology centers and the scientific community, Fondazione Italiana Linfomi (FIL) commissioned an analysis of the international follow-up approaches for long-term survivors after classical Hodgkin lymphoma (cHL) or diffuse large B-cell lymphoma (DLBCL). FIL set up multidisciplinary teams, representing all different skills relevant for cancer survivors. They conducted a series of systematic reviews focused on three main aspects: incidence of long-term toxicity; comparison of old or standard therapies and more recent ones; and evidence on specific follow-up approaches. The teams applied this framework to cardiological, endocrine-metabolic, neurological/cognitive, and psychological disorders, secondary cancers, fertility preservation, and lifestyles. Each team conducted comprehensive literature searches on PubMed, Embase and Cochrane Library databases up to 2020. Screening followed the PRISMA statement for reporting systematic reviews. The reviews report the results of this wide project covering the main areas of late toxicity and conditions in the long-term survival of cHL and DLBCL patients and their follow-up. From a clinical point of view, the series confirmed that the evidence on follow-up tended to focus on solid tumors with scant evidence on hematological malignancies.https://www.mdpi.com/2072-6694/13/12/2976cancer survivorshipHodgkin lymphomadiffuse large B-cell lymphomafollow-upsystematic review |
| spellingShingle | Chiara Gerardi Eleonora Allocati Carla Minoia Attilio Guarini Rita Banzi Long-Term Follow-Up of Classical Hodgkin Lymphoma and Diffuse Large B-Cell Lymphoma Survivors: Aims and Methodological Approach for Fondazione Italiana Linfomi Systematic Reviews Cancers cancer survivorship Hodgkin lymphoma diffuse large B-cell lymphoma follow-up systematic review |
| title | Long-Term Follow-Up of Classical Hodgkin Lymphoma and Diffuse Large B-Cell Lymphoma Survivors: Aims and Methodological Approach for Fondazione Italiana Linfomi Systematic Reviews |
| title_full | Long-Term Follow-Up of Classical Hodgkin Lymphoma and Diffuse Large B-Cell Lymphoma Survivors: Aims and Methodological Approach for Fondazione Italiana Linfomi Systematic Reviews |
| title_fullStr | Long-Term Follow-Up of Classical Hodgkin Lymphoma and Diffuse Large B-Cell Lymphoma Survivors: Aims and Methodological Approach for Fondazione Italiana Linfomi Systematic Reviews |
| title_full_unstemmed | Long-Term Follow-Up of Classical Hodgkin Lymphoma and Diffuse Large B-Cell Lymphoma Survivors: Aims and Methodological Approach for Fondazione Italiana Linfomi Systematic Reviews |
| title_short | Long-Term Follow-Up of Classical Hodgkin Lymphoma and Diffuse Large B-Cell Lymphoma Survivors: Aims and Methodological Approach for Fondazione Italiana Linfomi Systematic Reviews |
| title_sort | long term follow up of classical hodgkin lymphoma and diffuse large b cell lymphoma survivors aims and methodological approach for fondazione italiana linfomi systematic reviews |
| topic | cancer survivorship Hodgkin lymphoma diffuse large B-cell lymphoma follow-up systematic review |
| url | https://www.mdpi.com/2072-6694/13/12/2976 |
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