A Novel Hydroxylation Step in the Taxane Biosynthetic Pathway: A New Approach to Paclitaxel Production by Synthetic Biology
Engineered plant cell lines have the potential to achieve enhanced metabolite production rates, providing a high-yielding source of compounds of interest. Improving the production of taxanes, pharmacologically valuable secondary metabolites of Taxus spp., is hindered by an incomplete knowledge of th...
Main Authors: | Raul Sanchez-Muñoz, Edgar Perez-Mata, Lorena Almagro, Rosa M. Cusido, Mercedes Bonfill, Javier Palazon, Elisabeth Moyano |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-05-01
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Series: | Frontiers in Bioengineering and Biotechnology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fbioe.2020.00410/full |
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