Correlation between GenoType MTBDRplus Assay and Phenotypic Susceptibility Test for Prothionamide in Patients with Genotypic Isoniazid Resistance

Correlation between GenoType MTBDRplus Assay and Phenotypic Susceptibility Test for Prothionamide in Patients with Genotypic Isoniazid Resistance

Background The purpose of this study was to analyze the relationship between the gene mutation patterns by the GenoType MTBDRplus (MTBDRplus) assay and the phenotypic drug susceptibility test (pDST) results of isoniazid (INH) and prothionamide (Pto). Methods A total of 206 patients whose MTBDRp...

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Bibliographic Details
Main Authors: Joo Hee Lee, M.D., Kyung-Wook Jo, M.D., Ph.D., Tae Sun Shim, M.D., Ph.D.
Format: Article
Language:English
Published: The Korean Academy of Tuberculosis and Respiratory Diseases 2019-04-01
Series:Tuberculosis and Respiratory Diseases
Subjects:
katg protein
inha protein
isoniazid
prothionamide
genotype
biological assay
disease susceptibility
research design
mycobacterium tuberculosis
mycobacterium
Online Access:https://www.e-trd.org/search.php?where=aview&id=10.4046/trd.2018.0027&code=0003TRD&vmode=FULL

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