Hyaluronic acid plasma levels during high versus low tidal volume ventilation in a porcine sepsis model

Hyaluronic acid plasma levels during high versus low tidal volume ventilation in a porcine sepsis model

Background Shedding of the endothelial glycocalyx can be observed regularly during sepsis. Moreover, sepsis may be associated with acute respiratory distress syndrome (ARDS), which requires lung protective ventilation with the two cornerstones of application of low tidal volume and positive end-expi...

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Bibliographic Details
Main Authors: Rainer Thomas, Tanghua Liu, Arno Schad, Robert Ruemmler, Jens Kamuf, René Rissel, Thomas Ott, Matthias David, Erik K. Hartmann, Alexander Ziebart
Format: Article
Language:English
Published: PeerJ Inc. 2022-01-01
Series:PeerJ
Subjects:
Hyaluronic acid
Pig
Sepsis
Acute respiratory distress syndrome
ARDS
Lung protective ventilation
Online Access:https://peerj.com/articles/12649.pdf

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