Lockdown as an Intervention Measure to Mitigate the Spread of COVID-19: a modeling study

Abstract INTRODUCTION: This work aims to develop a biomathematical transmission model of COVID-19, in the State of Sergipe, Brazil, to estimate the distribution of cases over time and project the impact on the spread of the epidemic outbreak due to interventions and control measures over the local...

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Main Authors: Aédson Nascimento Góis, Estevão Esmi Laureano, David da Silva Santos, Daniel Eduardo Sánchez, Luiz Fernando Souza, Rita de Cássia Almeida Vieira, Jussiely Cunha Oliveira, Eduesley Santana-Santos
Format: Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2020-10-01
Series:Revista da Sociedade Brasileira de Medicina Tropical
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822020000100368&tlng=en
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author Aédson Nascimento Góis
Estevão Esmi Laureano
David da Silva Santos
Daniel Eduardo Sánchez
Luiz Fernando Souza
Rita de Cássia Almeida Vieira
Jussiely Cunha Oliveira
Eduesley Santana-Santos
author_facet Aédson Nascimento Góis
Estevão Esmi Laureano
David da Silva Santos
Daniel Eduardo Sánchez
Luiz Fernando Souza
Rita de Cássia Almeida Vieira
Jussiely Cunha Oliveira
Eduesley Santana-Santos
author_sort Aédson Nascimento Góis
collection DOAJ
description Abstract INTRODUCTION: This work aims to develop a biomathematical transmission model of COVID-19, in the State of Sergipe, Brazil, to estimate the distribution of cases over time and project the impact on the spread of the epidemic outbreak due to interventions and control measures over the local population. METHODS: This is an epidemiological mathematical modeling study conducted to analyze the dynamics of the accumulated cases of COVID-19, which used a logistic growth model that adds a term of withdrawal of individuals as a control measure. Three possible COVID-19 propagation scenarios were simulated based on three different rates of withdrawal of individuals. They were adjusted with real data of the infected and measures of control over the population. RESULTS: The lockdown would be the best scenario, with a lower incidence of infected people, when compared to the other measures. The number of infected people would grow slowly over the months, and the number of symptomatic individuals in this scenario would be 40,265 cases. We noticed that the State of Sergipe is still in the initial stage of the disease in the scenarios. It was possible to observe that the peak of cases and the equilibrium, in the current situation of social isolation, will occur when reaching the new support capacity, at the end of August in approximately 1,171,353 infected individuals. CONCLUSIONS: We established that lockdown is the intervention with the highest ability to mitigate the spread of the virus among the population.
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spelling doaj.art-66eee30074bb4a0e9e08a8b49c319c022022-12-22T00:28:52ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-98492020-10-015310.1590/0037-8682-0417-2020Lockdown as an Intervention Measure to Mitigate the Spread of COVID-19: a modeling studyAédson Nascimento Góishttps://orcid.org/0000-0002-9118-6247Estevão Esmi LaureanoDavid da Silva SantosDaniel Eduardo SánchezLuiz Fernando SouzaRita de Cássia Almeida VieiraJussiely Cunha OliveiraEduesley Santana-SantosAbstract INTRODUCTION: This work aims to develop a biomathematical transmission model of COVID-19, in the State of Sergipe, Brazil, to estimate the distribution of cases over time and project the impact on the spread of the epidemic outbreak due to interventions and control measures over the local population. METHODS: This is an epidemiological mathematical modeling study conducted to analyze the dynamics of the accumulated cases of COVID-19, which used a logistic growth model that adds a term of withdrawal of individuals as a control measure. Three possible COVID-19 propagation scenarios were simulated based on three different rates of withdrawal of individuals. They were adjusted with real data of the infected and measures of control over the population. RESULTS: The lockdown would be the best scenario, with a lower incidence of infected people, when compared to the other measures. The number of infected people would grow slowly over the months, and the number of symptomatic individuals in this scenario would be 40,265 cases. We noticed that the State of Sergipe is still in the initial stage of the disease in the scenarios. It was possible to observe that the peak of cases and the equilibrium, in the current situation of social isolation, will occur when reaching the new support capacity, at the end of August in approximately 1,171,353 infected individuals. CONCLUSIONS: We established that lockdown is the intervention with the highest ability to mitigate the spread of the virus among the population.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822020000100368&tlng=enCOVID-19Coronavirus infectionSocial isolationEpidemiology
spellingShingle Aédson Nascimento Góis
Estevão Esmi Laureano
David da Silva Santos
Daniel Eduardo Sánchez
Luiz Fernando Souza
Rita de Cássia Almeida Vieira
Jussiely Cunha Oliveira
Eduesley Santana-Santos
Lockdown as an Intervention Measure to Mitigate the Spread of COVID-19: a modeling study
Revista da Sociedade Brasileira de Medicina Tropical
COVID-19
Coronavirus infection
Social isolation
Epidemiology
title Lockdown as an Intervention Measure to Mitigate the Spread of COVID-19: a modeling study
title_full Lockdown as an Intervention Measure to Mitigate the Spread of COVID-19: a modeling study
title_fullStr Lockdown as an Intervention Measure to Mitigate the Spread of COVID-19: a modeling study
title_full_unstemmed Lockdown as an Intervention Measure to Mitigate the Spread of COVID-19: a modeling study
title_short Lockdown as an Intervention Measure to Mitigate the Spread of COVID-19: a modeling study
title_sort lockdown as an intervention measure to mitigate the spread of covid 19 a modeling study
topic COVID-19
Coronavirus infection
Social isolation
Epidemiology
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822020000100368&tlng=en
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