THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTS
In the last 10 years the World has increased significantly the frequency of joint replacement in patients with coronary artery disease. Coronary angioplasty with stenting significantly improve the capacity and effectiveness of the treatment of coronary artery disease. However, an important factor li...
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Format: | Article |
Language: | English |
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Siberian State Medical University (Tomsk)
2015-02-01
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Series: | Бюллетень сибирской медицины |
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Online Access: | https://bulletin.ssmu.ru/jour/article/view/146 |
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author | S. I. Vintizenko L. M. Ogorodova K. Yu. Rukin I. V. Petrova |
author_facet | S. I. Vintizenko L. M. Ogorodova K. Yu. Rukin I. V. Petrova |
author_sort | S. I. Vintizenko |
collection | DOAJ |
description | In the last 10 years the World has increased significantly the frequency of joint replacement in patients with coronary artery disease. Coronary angioplasty with stenting significantly improve the capacity and effectiveness of the treatment of coronary artery disease. However, an important factor limiting the effectiveness of endovascular treatment of restenosis remains the stented area.The article presents an overview of the most studied gene polymorphisms of hemostasis, inflammation system, the renin-angiotensin system, endothelial nitric oxide synthase, which can play a key role in the development of in-stent restenosis. Research in this area are significant and may help in understanding the mechanisms and risk stratification of restenosis after angioplasty. |
first_indexed | 2024-04-10T01:07:30Z |
format | Article |
id | doaj.art-66efb3eff12643899529971c93075732 |
institution | Directory Open Access Journal |
issn | 1682-0363 1819-3684 |
language | English |
last_indexed | 2024-04-10T01:07:30Z |
publishDate | 2015-02-01 |
publisher | Siberian State Medical University (Tomsk) |
record_format | Article |
series | Бюллетень сибирской медицины |
spelling | doaj.art-66efb3eff12643899529971c930757322023-03-13T09:58:21ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842015-02-0114110210910.20538/1682-0363-2015-1-102-109144THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTSS. I. Vintizenko0L. M. Ogorodova1K. Yu. Rukin2I. V. Petrova3Научно-исследовательский институт кардиологии, ТомскСибирский государственный медицинский университет, ТомскСибирский государственный медицинский университет, ТомскСибирский государственный медицинский университет, ТомскIn the last 10 years the World has increased significantly the frequency of joint replacement in patients with coronary artery disease. Coronary angioplasty with stenting significantly improve the capacity and effectiveness of the treatment of coronary artery disease. However, an important factor limiting the effectiveness of endovascular treatment of restenosis remains the stented area.The article presents an overview of the most studied gene polymorphisms of hemostasis, inflammation system, the renin-angiotensin system, endothelial nitric oxide synthase, which can play a key role in the development of in-stent restenosis. Research in this area are significant and may help in understanding the mechanisms and risk stratification of restenosis after angioplasty.https://bulletin.ssmu.ru/jour/article/view/146рестенознегативное ремоделированиегеныишемическая болезнь сердца |
spellingShingle | S. I. Vintizenko L. M. Ogorodova K. Yu. Rukin I. V. Petrova THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTS Бюллетень сибирской медицины рестеноз негативное ремоделирование гены ишемическая болезнь сердца |
title | THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTS |
title_full | THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTS |
title_fullStr | THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTS |
title_full_unstemmed | THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTS |
title_short | THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTS |
title_sort | role of genetic factors in the mechanism of coronary artery remodeling after implantation of stents |
topic | рестеноз негативное ремоделирование гены ишемическая болезнь сердца |
url | https://bulletin.ssmu.ru/jour/article/view/146 |
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