THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTS

In the last 10 years the World has increased significantly the frequency of joint replacement in patients with coronary artery disease. Coronary angioplasty with stenting significantly improve the capacity and effectiveness of the treatment of coronary artery disease. However, an important factor li...

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Main Authors: S. I. Vintizenko, L. M. Ogorodova, K. Yu. Rukin, I. V. Petrova
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2015-02-01
Series:Бюллетень сибирской медицины
Subjects:
Online Access:https://bulletin.ssmu.ru/jour/article/view/146
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author S. I. Vintizenko
L. M. Ogorodova
K. Yu. Rukin
I. V. Petrova
author_facet S. I. Vintizenko
L. M. Ogorodova
K. Yu. Rukin
I. V. Petrova
author_sort S. I. Vintizenko
collection DOAJ
description In the last 10 years the World has increased significantly the frequency of joint replacement in patients with coronary artery disease. Coronary angioplasty with stenting significantly improve the capacity and effectiveness of the treatment of coronary artery disease. However, an important factor limiting the effectiveness of endovascular treatment of restenosis remains the stented area.The article presents an overview of the most studied gene polymorphisms of hemostasis, inflammation system, the renin-angiotensin system, endothelial nitric oxide synthase, which can play a key role in the development of in-stent restenosis. Research in this area are significant and may help in understanding the mechanisms and risk stratification of restenosis after angioplasty.
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spelling doaj.art-66efb3eff12643899529971c930757322023-03-13T09:58:21ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842015-02-0114110210910.20538/1682-0363-2015-1-102-109144THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTSS. I. Vintizenko0L. M. Ogorodova1K. Yu. Rukin2I. V. Petrova3Научно-исследовательский институт кардиологии, ТомскСибирский государственный медицинский университет, ТомскСибирский государственный медицинский университет, ТомскСибирский государственный медицинский университет, ТомскIn the last 10 years the World has increased significantly the frequency of joint replacement in patients with coronary artery disease. Coronary angioplasty with stenting significantly improve the capacity and effectiveness of the treatment of coronary artery disease. However, an important factor limiting the effectiveness of endovascular treatment of restenosis remains the stented area.The article presents an overview of the most studied gene polymorphisms of hemostasis, inflammation system, the renin-angiotensin system, endothelial nitric oxide synthase, which can play a key role in the development of in-stent restenosis. Research in this area are significant and may help in understanding the mechanisms and risk stratification of restenosis after angioplasty.https://bulletin.ssmu.ru/jour/article/view/146рестенознегативное ремоделированиегеныишемическая болезнь сердца
spellingShingle S. I. Vintizenko
L. M. Ogorodova
K. Yu. Rukin
I. V. Petrova
THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTS
Бюллетень сибирской медицины
рестеноз
негативное ремоделирование
гены
ишемическая болезнь сердца
title THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTS
title_full THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTS
title_fullStr THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTS
title_full_unstemmed THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTS
title_short THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTS
title_sort role of genetic factors in the mechanism of coronary artery remodeling after implantation of stents
topic рестеноз
негативное ремоделирование
гены
ишемическая болезнь сердца
url https://bulletin.ssmu.ru/jour/article/view/146
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