Tissue Distribution and Regulation of the Small Sar1b GTPase in Mice

Tissue Distribution and Regulation of the Small Sar1b GTPase in Mice

Background/Aims: Sar1b GTPase (Sar1b) represents an obligatory component of COPII vesicles that bud from the endoplasmic reticulum to transport proteins to the Golgi apparatus. Its genetic mutations lead to a severe disorder known as chylomicron retention disease. Despite growing knowledge on Sar1b,...

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Bibliographic Details
Main Authors: Valérie Marcil, Ernest Seidman, Daniel Sinnett, Rocio Sanchez, Schohraya Spahis, Alain Sané, Emile Levy
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-06-01
Series:Cellular Physiology and Biochemistry
Subjects:
Gene expression
Transgenic mice
Sar1b GTPase
Coat protein complex II vesicles
Online Access:http://www.karger.com/Article/FullText/362960

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