Recent Progress of SERS Nanoprobe for pH Detecting and Its Application in Biological Imaging
As pH value almost affects the function of cells and organisms in all aspects, in biology, biochemical and many other research fields, it is necessary to apply simple, intuitive, sensitive, stable detection of pH and base characteristics inside and outside the cell. Therefore, many research groups h...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-08-01
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| Series: | Biosensors |
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| Online Access: | https://www.mdpi.com/2079-6374/11/8/282 |
| _version_ | 1797524509984555008 |
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| author | Lei Zhang Qianqian Zhao Zhitao Jiang Jingjing Shen Weibing Wu Xingfen Liu Quli Fan Wei Huang |
| author_facet | Lei Zhang Qianqian Zhao Zhitao Jiang Jingjing Shen Weibing Wu Xingfen Liu Quli Fan Wei Huang |
| author_sort | Lei Zhang |
| collection | DOAJ |
| description | As pH value almost affects the function of cells and organisms in all aspects, in biology, biochemical and many other research fields, it is necessary to apply simple, intuitive, sensitive, stable detection of pH and base characteristics inside and outside the cell. Therefore, many research groups have explored the design and application of pH probes based on surface enhanced Raman scattering (SERS). In this review article, we discussed the basic theoretical background of explaining the working mechanism of pH SERS sensors, and also briefly described the significance of cell pH measurement, and simply classified and summarized the factors that affected the performance of pH SERS probes. Some applications of pH probes based on surface enhanced Raman scattering in intracellular and extracellular pH imaging and the combination of other analytical detection techniques are described. Finally, the development prospect of this field is presented. |
| first_indexed | 2024-03-10T08:58:25Z |
| format | Article |
| id | doaj.art-66f3781e2a6c4ba982646f31cafabb1a |
| institution | Directory Open Access Journal |
| issn | 2079-6374 |
| language | English |
| last_indexed | 2024-03-10T08:58:25Z |
| publishDate | 2021-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biosensors |
| spelling | doaj.art-66f3781e2a6c4ba982646f31cafabb1a2023-11-22T06:57:49ZengMDPI AGBiosensors2079-63742021-08-0111828210.3390/bios11080282Recent Progress of SERS Nanoprobe for pH Detecting and Its Application in Biological ImagingLei Zhang0Qianqian Zhao1Zhitao Jiang2Jingjing Shen3Weibing Wu4Xingfen Liu5Quli Fan6Wei Huang7Institute of Advanced Materials (IAM), Nanjing University of Posts and Telecommunications (NUPT), 9 Wenyuan Road, Nanjing 210023, ChinaInstitute of Advanced Materials (IAM), Nanjing University of Posts and Telecommunications (NUPT), 9 Wenyuan Road, Nanjing 210023, ChinaInstitute of Advanced Materials (IAM), Nanjing University of Posts and Telecommunications (NUPT), 9 Wenyuan Road, Nanjing 210023, ChinaInstitute of Advanced Materials (IAM), Nanjing University of Posts and Telecommunications (NUPT), 9 Wenyuan Road, Nanjing 210023, ChinaJiangsu Provincial Key Lab of Pulp & Paper Science & Technology, Nanjing Forestry University, 159 Longpan Road, Nanjing 210023, ChinaInstitute of Advanced Materials (IAM), Nanjing University of Posts and Telecommunications (NUPT), 9 Wenyuan Road, Nanjing 210023, ChinaInstitute of Advanced Materials (IAM), Nanjing University of Posts and Telecommunications (NUPT), 9 Wenyuan Road, Nanjing 210023, ChinaInstitute of Advanced Materials (IAM), Nanjing University of Posts and Telecommunications (NUPT), 9 Wenyuan Road, Nanjing 210023, ChinaAs pH value almost affects the function of cells and organisms in all aspects, in biology, biochemical and many other research fields, it is necessary to apply simple, intuitive, sensitive, stable detection of pH and base characteristics inside and outside the cell. Therefore, many research groups have explored the design and application of pH probes based on surface enhanced Raman scattering (SERS). In this review article, we discussed the basic theoretical background of explaining the working mechanism of pH SERS sensors, and also briefly described the significance of cell pH measurement, and simply classified and summarized the factors that affected the performance of pH SERS probes. Some applications of pH probes based on surface enhanced Raman scattering in intracellular and extracellular pH imaging and the combination of other analytical detection techniques are described. Finally, the development prospect of this field is presented.https://www.mdpi.com/2079-6374/11/8/282pHSERSprobedetectionimaging |
| spellingShingle | Lei Zhang Qianqian Zhao Zhitao Jiang Jingjing Shen Weibing Wu Xingfen Liu Quli Fan Wei Huang Recent Progress of SERS Nanoprobe for pH Detecting and Its Application in Biological Imaging Biosensors pH SERS probe detection imaging |
| title | Recent Progress of SERS Nanoprobe for pH Detecting and Its Application in Biological Imaging |
| title_full | Recent Progress of SERS Nanoprobe for pH Detecting and Its Application in Biological Imaging |
| title_fullStr | Recent Progress of SERS Nanoprobe for pH Detecting and Its Application in Biological Imaging |
| title_full_unstemmed | Recent Progress of SERS Nanoprobe for pH Detecting and Its Application in Biological Imaging |
| title_short | Recent Progress of SERS Nanoprobe for pH Detecting and Its Application in Biological Imaging |
| title_sort | recent progress of sers nanoprobe for ph detecting and its application in biological imaging |
| topic | pH SERS probe detection imaging |
| url | https://www.mdpi.com/2079-6374/11/8/282 |
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