Immediate and six months clinical and angiographic results of intracoronary paclitaxel-coated stent implantation – the Meo:DrugStar-1 study

Cihangir Uyan, Huseyin Arinc, Huseyin Gunduz, Ramazan AkdemirAbant Izzet Baysal University, Izzet Baysal Medical Faculty, Cardiology Department, Bolu, TurkeyAbstract: The study was conducted to evaluate the clinical and angiographic results of the implantation of the paclitaxel-eluting stent Meo:Dru...

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Main Authors: Cihangir Uyan, Huseyin Arinc, Huseyin Gunduz, Ramazan Akdemir
Format: Article
Language:English
Published: Dove Medical Press 2008-02-01
Series:Vascular Health and Risk Management
Online Access:https://www.dovepress.com/immediate-and-six-months-clinical-and-angiographic-results-of-intracor-peer-reviewed-article-VHRM
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author Cihangir Uyan
Huseyin Arinc
Huseyin Gunduz
Ramazan Akdemir
author_facet Cihangir Uyan
Huseyin Arinc
Huseyin Gunduz
Ramazan Akdemir
author_sort Cihangir Uyan
collection DOAJ
description Cihangir Uyan, Huseyin Arinc, Huseyin Gunduz, Ramazan AkdemirAbant Izzet Baysal University, Izzet Baysal Medical Faculty, Cardiology Department, Bolu, TurkeyAbstract: The study was conducted to evaluate the clinical and angiographic results of the implantation of the paclitaxel-eluting stent Meo:DrugStar ST in patients with symptomatic coronary artery disease. The Meo:DrugStar ST stent has a stainless steel stent platform with a homogenous non-biodegradable coating of paclitaxel mixed with a polyether-based biostable, monophase, and hemocompatible coating. Sixty patients with native coronary artery disease were included in the study. The Meo:DrugStar ST stents were implanted in 60 de novo lesions detected in these patients. Immediate and long-term clinical and angiographic follow-up results were evaluated. There was a high proportion of patients with hypertension (55%) according to JNC-VII. Mean stenosis ratio was 78 ± 13 %, mean implanted stent diameter was 3.0 ± 0.4 mm and mean length was 22 ± 5 mm. Restenosis was detected in 4 (10%) of those patients and 11 (27.5%) of 40 patients had insignificant amount of restenosis.The results of this study indicate a potential benefit of the Meo:DrugStar ST stent for the prevention of stent thrombosis and restenosis in these relatively high-risk patients.Keywords: Meo:DrugStar ST stent, paclitaxel drug-eluting stent, coronary artery disease
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spelling doaj.art-66f6529017e248208f9904062ea7bf072022-12-21T17:30:46ZengDove Medical PressVascular Health and Risk Management1178-20482008-02-01Volume 41731761582Immediate and six months clinical and angiographic results of intracoronary paclitaxel-coated stent implantation – the Meo:DrugStar-1 studyCihangir UyanHuseyin ArincHuseyin GunduzRamazan AkdemirCihangir Uyan, Huseyin Arinc, Huseyin Gunduz, Ramazan AkdemirAbant Izzet Baysal University, Izzet Baysal Medical Faculty, Cardiology Department, Bolu, TurkeyAbstract: The study was conducted to evaluate the clinical and angiographic results of the implantation of the paclitaxel-eluting stent Meo:DrugStar ST in patients with symptomatic coronary artery disease. The Meo:DrugStar ST stent has a stainless steel stent platform with a homogenous non-biodegradable coating of paclitaxel mixed with a polyether-based biostable, monophase, and hemocompatible coating. Sixty patients with native coronary artery disease were included in the study. The Meo:DrugStar ST stents were implanted in 60 de novo lesions detected in these patients. Immediate and long-term clinical and angiographic follow-up results were evaluated. There was a high proportion of patients with hypertension (55%) according to JNC-VII. Mean stenosis ratio was 78 ± 13 %, mean implanted stent diameter was 3.0 ± 0.4 mm and mean length was 22 ± 5 mm. Restenosis was detected in 4 (10%) of those patients and 11 (27.5%) of 40 patients had insignificant amount of restenosis.The results of this study indicate a potential benefit of the Meo:DrugStar ST stent for the prevention of stent thrombosis and restenosis in these relatively high-risk patients.Keywords: Meo:DrugStar ST stent, paclitaxel drug-eluting stent, coronary artery diseasehttps://www.dovepress.com/immediate-and-six-months-clinical-and-angiographic-results-of-intracor-peer-reviewed-article-VHRM
spellingShingle Cihangir Uyan
Huseyin Arinc
Huseyin Gunduz
Ramazan Akdemir
Immediate and six months clinical and angiographic results of intracoronary paclitaxel-coated stent implantation – the Meo:DrugStar-1 study
Vascular Health and Risk Management
title Immediate and six months clinical and angiographic results of intracoronary paclitaxel-coated stent implantation – the Meo:DrugStar-1 study
title_full Immediate and six months clinical and angiographic results of intracoronary paclitaxel-coated stent implantation – the Meo:DrugStar-1 study
title_fullStr Immediate and six months clinical and angiographic results of intracoronary paclitaxel-coated stent implantation – the Meo:DrugStar-1 study
title_full_unstemmed Immediate and six months clinical and angiographic results of intracoronary paclitaxel-coated stent implantation – the Meo:DrugStar-1 study
title_short Immediate and six months clinical and angiographic results of intracoronary paclitaxel-coated stent implantation – the Meo:DrugStar-1 study
title_sort immediate and six months clinical and angiographic results of intracoronary paclitaxel coated stent implantation ndash the meo drugstar 1 study
url https://www.dovepress.com/immediate-and-six-months-clinical-and-angiographic-results-of-intracor-peer-reviewed-article-VHRM
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