MiR-302d inhibits TGFB-induced EMT and promotes MET in primary human RPE cells

<h4>Purpose</h4> Transforming growth factor-beta (TGFB)-mediated epithelial-mesenchymal transition (EMT) plays a crucial role in the pathogenesis of retinal fibrosis, which is one of the leading causes of impaired vision. Current approaches to treating retinal fibrosis focus, among other...

Full description

Bibliographic Details
Main Authors: Xiaonan Hu, Maximilian Binter, Karsten Hufendiek, Jan Tode, Carsten Framme, Heiko Fuchs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704570/?tool=EBI