Fast Isolation of Flavonoids from the Endemic Species <i>Nolana ramosissima</i> I.M. Johnst and Its Endothelium-Independent Relaxation Effect in Rat Aorta

Fast Isolation of Flavonoids from the Endemic Species <i>Nolana ramosissima</i> I.M. Johnst and Its Endothelium-Independent Relaxation Effect in Rat Aorta

The infusion of the desertic plant <i>Nolana ramosissima</i> I.M. Johnst showed vascular smooth muscle relaxation in rat aorta and the presence of several phenolic compounds, which were detected by high resolution UHPLC-Orbitrap-HESI-MS. In addition, five flavonoids were rapidly isolated...

Full description

Bibliographic Details
Main Authors:	Fredi Cifuentes, Javier Palacios, Jorge Bórquez, Adrián Paredes, Claudio Parra, Alejandra Bravo, Mario J. Simirgiotis
Format:	Article
Language:	English
Published:	MDPI AG 2020-01-01
Series:	Molecules
Subjects:	mass spectrometry high-performance countercurrent chromatography flavonoids vasodilation chilean plants
Online Access:	https://www.mdpi.com/1420-3049/25/3/520

Similar Items

Chemical Fingerprinting, Isolation and Characterization of Polyphenol Compounds from <i>Heliotropium taltalense</i> (Phil.) I.M. Johnst and Its Endothelium-Dependent Vascular Relaxation Effect in Rat Aorta
by: Ruth E. Barrientos, et al.
Published: (2020-07-01)

UHPLC-MS Phenolic Fingerprinting, Aorta Endothelium Relaxation Effect, Antioxidant, and Enzyme Inhibition Activities of <i>Azara dentata Ruiz & Pav</i> Berries
by: Lucia Cuesta Ramos, et al.
Published: (2023-02-01)

Endothelium-dependent vasodilation by ferulic acid in aorta from chronic renal hypertensive rats
by: Seok Choi, et al.
Published: (2012-12-01)

Chemical Fingerprinting, Aorta Endothelium Relaxation Effect, and Enzymatic Inhibition of Canelo (<i>Drimys winteri</i> J. R. Forst. & G. Forst, (D.C) A. Gray, Family Winteraceae) Fruits
by: Ruth E. Barrientos, et al.
Published: (2023-07-01)

Countercurrent chromatography : apparatus, theory and application/
by: 319747 Conway, Walter D.
Published: (1990)

Modern countercurrent chromatography /
by: Conway, Walter D., et al.
Published: (1995)

Mechanisms involved in the endothelium-dependent vasodilatory effect of an ethyl acetate fraction of Cyathea phalerata Mart. in isolated rats’ aorta rings
by: Mariana Appel Hort, et al.
Published: (2020-07-01)

Separation of the Glycosylated Carotenoid Myxoxanthophyll from <i>Synechocystis Salina</i> by HPCCC and Evaluation of Its Antioxidant, Tyrosinase Inhibitory and Immune-Stimulating Properties
by: Michaela Nováková, et al.
Published: (2020-12-01)

Production of Fucoxanthin from <i>Phaeodactylum tricornutum</i> Using High Performance Countercurrent Chromatography Retaining Its FOXO3 Nuclear Translocation-Inducing Effect
by: Daniela Bárcenas-Pérez, et al.
Published: (2021-09-01)

The Passiflora tripartita (Banana Passion) Fruit: A Source of Bioactive Flavonoid C-Glycosides Isolated by HSCCC and Characterized by HPLC–DAD–ESI/MS/MS
by: Mario J. Simirgiotis, et al.
Published: (2013-01-01)

Pu-Erh Tea Relaxes the Thoracic Aorta of Rats by Reducing Intracellular Calcium
by: Dan Luo, et al.
Published: (2019-11-01)

Novel Oxime Synthesized from a Natural Product of <i>Senecio nutans</i> SCh. Bip. (Asteraceae) Enhances Vascular Relaxation in Rats by an Endothelium-Independent Mechanism
by: Javier Palacios, et al.
Published: (2022-05-01)

Nitric-Oxide-Mediated Vasodilation of Bioactive Compounds Isolated from <i>Hypericum revolutum</i> in Rat Aorta
by: Hossam M. Abdallah, et al.
Published: (2021-06-01)

Endothelium-Independent Vasodilatory Effects of Isodillapiolglycol Isolated from <i>Ostericum citriodorum</i>
by: Tengshuo Luo, et al.
Published: (2020-02-01)

NOMENCLATURAL CHANGES IN NOLANA (NOLANEAE, SOLANACEAE) CAMBIOS NOMENCLATURALES EN NOLANA (NOLANEAE, SOLANACEAE)
by: Michael O Dillon
Published: (2009-01-01)

A Review of Endothelium-Dependent and -Independent Vasodilation Induced by Phytochemicals in Isolated Rat Aorta
by: Marcela Knox, et al.
Published: (2019-08-01)

Role of non-nitric oxide non-prostaglandin endothelium-derived relaxing factor(s) in bradykinin vasodilation
by: A.C. Resende, et al.
Published: (1998-09-01)

Secondary Metabolites of Plants as Modulators of Endothelium Functions
by: Anna Bartáková, et al.
Published: (2021-03-01)

Kinetic modeling of countercurrent saccharification
by: Chao Liang, et al.
Published: (2019-07-01)

Vasorelaxant Effects of <i>Syzygium samarangense</i> (Blume) Merr. and L.M.Perry Extract Are Mediated by NO/cGMP Pathway in Isolated Rat Thoracic Aorta
by: Noura A. Hassan, et al.
Published: (2022-10-01)

Effect of Anthocyanin-Rich Extract of Sour Cherry for Hyperglycemia-Induced Inflammatory Response and Impaired Endothelium-Dependent Vasodilation
by: Arnold Markovics, et al.
Published: (2020-11-01)

VASOMOTOR FUNCTION OF THE ENDOTHELIUM IN PATIENTS WITH CHRONIC KIDNEY DISEASE AND HYPERTENSION
by: N. V. Demikhova, et al.
Published: (2017-12-01)

Rutamarin: Efficient Liquid–Liquid Chromatographic Isolation from <i>Ruta graveolens</i> L. and Evaluation of Its In Vitro and In Silico MAO-B Inhibitory Activity
by: Ewelina Kozioł, et al.
Published: (2020-06-01)

White Wine—Induced Endothelium-Dependent Vasorelaxation in Sprague-Dawley Rats
by: Zrinka Mihaljević, et al.
Published: (2022-05-01)

Assessment of endothelium: Dependent vasodilation with a non-invasive method in patients with preeclampsia compared to normotensive pregnant women
by: Seyedeh Zahra Allameh, et al.
Published: (2014-01-01)

Decoding Dynamic Ca2+ Signaling in the Vascular Endothelium
by: Mark Stephen Taylor, et al.
Published: (2014-11-01)

In Silico-Assisted Isolation of <i>trans</i>-Resveratrol and <i>trans</i>-ε-Viniferin from Grapevine Canes and Their Sustainable Extraction Using Natural Deep Eutectic Solvents (NADES)
by: Mats Kiene, et al.
Published: (2023-11-01)

Mechanisms Underlying Vasorelaxation Induced in Rat Aorta by Galetin 3,6-Dimethyl Ether, a Flavonoid from Piptadenia stipulacea (Benth.) Ducke
by: Cibério L. Macêdo, et al.
Published: (2014-11-01)

The Potential Involvement of an ATP-Dependent Potassium Channel-Opening Mechanism in the Smooth Muscle Relaxant Properties of <i>Tamarix dioica Roxb</i>.
by: Syeda Madiha Imtiaz, et al.
Published: (2019-11-01)

Dispersed Mobile-Phase Countercurrent Chromatography
by: Timothy Yiu-Cheong Ho, et al.
Published: (2016-11-01)

Extent and Energetics of the Hawaiian Lee Countercurrent
by: Rick Lumpkin, et al.
Published: (2013-03-01)

Discovering the Next-Generation Plant Protection Products: A Proof-of-Concept via the Isolation and Bioactivity Assessment of the Olive Tree Endophyte <i>Bacillus</i> sp. PTA13 Lipopeptides
by: Evgenia-Anna Papadopoulou, et al.
Published: (2021-12-01)

MILDRONATE EFFECT ON ENDOTHELIUM-DEPENDENT VASODILATION IN PATIENTS WITH CHRONIC HEART FAILURE: DOUBLE BLIND CROSSOVER STUDY
by: L. G. Voronkov, et al.
Published: (2016-01-01)

Dehydroabietic Acid Isolated from Commiphora opobalsamum Causes Endothelium-Dependent Relaxation of Pulmonary Artery via PI3K/Akt-eNOS Signaling Pathway
by: Wenyan Gao, et al.
Published: (2014-06-01)

Ionic radiocontrast inhibits endothelium-dependent vasodilation of the canine renal artery in vitro: possible mechanism of renal failure following contrast medium infusion
by: B. Discigil, et al.
Published: (2004-02-01)

The GPR18 Agonist PSB-KD-107 Exerts Endothelium-Dependent Vasorelaxant Effects
by: Magdalena Kotańska, et al.
Published: (2021-08-01)

Swimbladder Function in the European Eel <i>Anguilla anguilla</i>
by: Bernd Pelster
Published: (2023-02-01)

Evaluation of Anti-<i>Trypanosoma cruzi</i> Activity of Chemical Constituents from <i>Baccharis sphenophylla</i> Isolated Using High-Performance Countercurrent Chromatography
by: Matheus L. Silva, et al.
Published: (2023-12-01)

Spironolactone Induces Vasodilation by Endothelium-Dependent Mechanisms Involving NO and by Endothelium-Independent Mechanisms Blocking Ca<sup>2+</sup> Channels
by: Margarida Lorigo, et al.
Published: (2024-03-01)

Post-exercise Endothelium-Dependent Vasodilation Is Dependent on Training Status
by: L. V. Kapilevich, et al.
Published: (2020-05-01)