Genome-wide association studies of polygenic risk score-derived phenotypes may lead to inflated false positive rates
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-03-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-29428-9 |
| _version_ | 1797864693962899456 |
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| author | Emil Uffelmann Danielle Posthuma Wouter J. Peyrot |
| author_facet | Emil Uffelmann Danielle Posthuma Wouter J. Peyrot |
| author_sort | Emil Uffelmann |
| collection | DOAJ |
| first_indexed | 2024-04-09T22:56:07Z |
| format | Article |
| id | doaj.art-66fb508b6f61474d85b0ead88e965124 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-09T22:56:07Z |
| publishDate | 2023-03-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-66fb508b6f61474d85b0ead88e9651242023-03-22T11:13:56ZengNature PortfolioScientific Reports2045-23222023-03-011311410.1038/s41598-023-29428-9Genome-wide association studies of polygenic risk score-derived phenotypes may lead to inflated false positive ratesEmil Uffelmann0Danielle Posthuma1Wouter J. Peyrot2Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit AmsterdamDepartment of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit AmsterdamDepartment of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdamhttps://doi.org/10.1038/s41598-023-29428-9 |
| spellingShingle | Emil Uffelmann Danielle Posthuma Wouter J. Peyrot Genome-wide association studies of polygenic risk score-derived phenotypes may lead to inflated false positive rates Scientific Reports |
| title | Genome-wide association studies of polygenic risk score-derived phenotypes may lead to inflated false positive rates |
| title_full | Genome-wide association studies of polygenic risk score-derived phenotypes may lead to inflated false positive rates |
| title_fullStr | Genome-wide association studies of polygenic risk score-derived phenotypes may lead to inflated false positive rates |
| title_full_unstemmed | Genome-wide association studies of polygenic risk score-derived phenotypes may lead to inflated false positive rates |
| title_short | Genome-wide association studies of polygenic risk score-derived phenotypes may lead to inflated false positive rates |
| title_sort | genome wide association studies of polygenic risk score derived phenotypes may lead to inflated false positive rates |
| url | https://doi.org/10.1038/s41598-023-29428-9 |
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