Development and Characterization of Solid Dispersion for Dissolution Improvement of Furosemide by Cogrinding Method

Development and Characterization of Solid Dispersion for Dissolution Improvement of Furosemide by Cogrinding Method

Purpose: The purpose of this study was to prepare and characterize solid dispersion formulation of furosemide to enhance dissolution rate. Methods: Solid dispersions with different drug: carrier ratios were prepared by cogrinding method using crospovidone and microcrystalline cellulose as carrier....

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Bibliographic Details
Main Authors: Mohammad Reza Siahi-Shadbad, Saeed Ghanbarzadeh, Mohammad Barzegar-Jalali, Hadi Valizadeh, Alireza Taherpoor, Ghobad Mohammadi, Azim Barzegar-Jalali, Khosro Adibkia
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2014-12-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Furosemide
Solid dispersion
Dissolution rate
Release kinetic
Online Access:http://journals.tbzmed.ac.ir/APB/Manuscript/APB-4-391.pdf

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