A dysbiotic mycobiome dominated by Candida albicans is identified within oral squamous-cell carcinomas

A dysbiotic mycobiome dominated by Candida albicans is identified within oral squamous-cell carcinomas

The aim of this study was to characterize the mycobiome associated with oral squamous-cell carcinoma (OSCC). DNA was extracted from 52 tissue biopsies (cases: 25 OSCC; controls: 27 intra-oral fibro-epithelial polyps [FEP]) and sequenced for the fungal internal transcribed spacer 2 region using Illum...

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Bibliographic Details
Main Authors: Manosha Perera, Nezar Noor Al-hebshi, Irosha Perera, Deepak Ipe, Glen C. Ulett, David J. Speicher, Tsute Chen, Newell W. Johnson
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Journal of Oral Microbiology
Subjects:
Fungi
mycobiome
carcinoma
high-throughput nucleotide sequencing
DNA ribosomal spacer
microbiome
mouth
squamous cell
Online Access:http://dx.doi.org/10.1080/20002297.2017.1385369

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