Green synthesis of gold nanoparticles as an effective opportunity for cancer treatment

Nanotechnology has proven to be a technology capable of generating anti-cancer nanoparticles in an environmentally friendly approach. Nanoparticles are usually created using a variety of processes that have a detrimental effect on the environment. Incorporating plant extracts with nanoparticles is a...

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Main Authors: Ali S. Abed, Yousif H. Khalaf, Ahmed Mishaal Mohammed
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Results in Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715623000875
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author Ali S. Abed
Yousif H. Khalaf
Ahmed Mishaal Mohammed
author_facet Ali S. Abed
Yousif H. Khalaf
Ahmed Mishaal Mohammed
author_sort Ali S. Abed
collection DOAJ
description Nanotechnology has proven to be a technology capable of generating anti-cancer nanoparticles in an environmentally friendly approach. Nanoparticles are usually created using a variety of processes that have a detrimental effect on the environment. Incorporating plant extracts with nanoparticles is an alternative, conservative method. In our research, gold nanoparticles were prepared by two aqueous extracts of Ziziphus spina-christi leaves and Cordia myxa L. leaves, and diagnosed using TEM, FE-SEM and AFM. The ability of gold nanoparticles as an anti-breast cancer agent was tested against MCF-7 cell line in synergistic with near-infrared radiation (NIR) at 808 nm. It was found that radiation enhances the properties of gold nanoparticles as a cancer treatment by converting the absorbed light into heat in a short time through a series of non-radiative processes.
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spelling doaj.art-670c26df969e47d6bc1f739568f38fea2023-06-21T06:52:15ZengElsevierResults in Chemistry2211-71562023-01-015100848Green synthesis of gold nanoparticles as an effective opportunity for cancer treatmentAli S. Abed0Yousif H. Khalaf1Ahmed Mishaal Mohammed2Department of Chemistry, College of Science, University Of Anbar, Ramadi, IraqDepartment of Clinical Lab. Sciences, College of Pharmacy, University Of Anbar, Ramadi, IraqDepartment of Chemistry, College of Science, University Of Anbar, Ramadi, Iraq; Corresponding author.Nanotechnology has proven to be a technology capable of generating anti-cancer nanoparticles in an environmentally friendly approach. Nanoparticles are usually created using a variety of processes that have a detrimental effect on the environment. Incorporating plant extracts with nanoparticles is an alternative, conservative method. In our research, gold nanoparticles were prepared by two aqueous extracts of Ziziphus spina-christi leaves and Cordia myxa L. leaves, and diagnosed using TEM, FE-SEM and AFM. The ability of gold nanoparticles as an anti-breast cancer agent was tested against MCF-7 cell line in synergistic with near-infrared radiation (NIR) at 808 nm. It was found that radiation enhances the properties of gold nanoparticles as a cancer treatment by converting the absorbed light into heat in a short time through a series of non-radiative processes.http://www.sciencedirect.com/science/article/pii/S2211715623000875BiosynthesisNanoparticlesCancerAuNPsCytotoxicity
spellingShingle Ali S. Abed
Yousif H. Khalaf
Ahmed Mishaal Mohammed
Green synthesis of gold nanoparticles as an effective opportunity for cancer treatment
Results in Chemistry
Biosynthesis
Nanoparticles
Cancer
AuNPs
Cytotoxicity
title Green synthesis of gold nanoparticles as an effective opportunity for cancer treatment
title_full Green synthesis of gold nanoparticles as an effective opportunity for cancer treatment
title_fullStr Green synthesis of gold nanoparticles as an effective opportunity for cancer treatment
title_full_unstemmed Green synthesis of gold nanoparticles as an effective opportunity for cancer treatment
title_short Green synthesis of gold nanoparticles as an effective opportunity for cancer treatment
title_sort green synthesis of gold nanoparticles as an effective opportunity for cancer treatment
topic Biosynthesis
Nanoparticles
Cancer
AuNPs
Cytotoxicity
url http://www.sciencedirect.com/science/article/pii/S2211715623000875
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