Comparison of the Protective Effects of Ginsenosides Rb1 and Rg1 on Improving Cognitive Deficits in SAMP8 Mice Based on Anti-Neuroinflammation Mechanism

Comparison of the Protective Effects of Ginsenosides Rb1 and Rg1 on Improving Cognitive Deficits in SAMP8 Mice Based on Anti-Neuroinflammation Mechanism

This present study was designed to investigate the different effects of ginsenosides Rb1 and Rg1 on improving cognitive deficits in 4-month-old SAMP8 mice. Mice were divided into six groups, including the SAMP8 group, the SAMP8 + Donepezil (1.6 mg/kg) group, the SAMP8 + Rb1 (30 and 60 µmol/kg), and...

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Bibliographic Details
Main Authors: Yujie Yang, Shanshan Li, Hong Huang, Jingwei Lv, Shanguang Chen, Alberto Carlos Pires Dias, Yujiao Li, Xinmin Liu, Qiong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Pharmacology
Subjects:
ginsenoside Rb1
ginsenoside Rg1
Alzheimer's disease
SAMP8 mice
neuroinflammation
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00834/full

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