Reciprocal Crosstalk between Dendritic Cells and Natural Killer T Cells: Mechanisms and Therapeutic Potential

Reciprocal Crosstalk between Dendritic Cells and Natural Killer T Cells: Mechanisms and Therapeutic Potential

Natural killer T cells carrying a highly conserved, semi-invariant T cell receptor (TCR) [invariant natural killer T (iNKT) cells] are a subset of unconventional T lymphocytes that recognize glycolipids presented by CD1d molecules. Although CD1d is expressed on a variety of hematopoietic and non-hem...

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Bibliographic Details
Main Authors: Christian W. Keller, Stefan Freigang, Jan D. Lünemann
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Immunology
Subjects:
dendritic cells
natural killer T cells
CD1d
glycolipids
immunotherapy
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00570/full

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