Microdiversity of Enterococcus faecalis isolates in cases of infective endocarditis: selection of non-synonymous mutations and large deletions is associated with phenotypic modifications

Microdiversity of Enterococcus faecalis isolates in cases of infective endocarditis: selection of non-synonymous mutations and large deletions is associated with phenotypic modifications

Context: Today, infective endocarditis (IE) caused by Enterococcus faecalis represents 10% of all IE and is marked by its difficult management and the frequency of relapses. Although the precise reasons for that remain to be elucidated, the evolution of the culprit strain under selective pressure th...

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Bibliographic Details
Main Authors: G. Royer, L. Roisin, V. Demontant, S. Lo, L. Coutte, P. Lim, J. M. Pawlotsky, H. Jacquier, R. Lepeule, C. Rodriguez, P. L. Woerther
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Emerging Microbes and Infections
Subjects:
Enterococcus faecalis
infective endocarditis
whole genome sequencing
microdiversity
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2021.1924865

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