Evaluation of living liver donors using contrast enhanced multidetector CT – The radiologists impact on donor selection

<p>Abstract</p> <p>Background</p> <p>Living donor liver transplantation (LDLT) is a valuable and legitimate treatment for patients with end-stage liver disease. Computed tomography (CT) has proven to be an important tool in the process of donor evaluation. The purpose o...

Full description

Bibliographic Details
Main Authors: Ringe Kristina, Ringe Bastian, von Falck Christian, Shin Hoen-oh, Becker Thomas, Pfister Eva-Doreen, Wacker Frank, Ringe Burckhardt
Format: Article
Language:English
Published: BMC 2012-07-01
Series:BMC Medical Imaging
Subjects:
Online Access:http://www.biomedcentral.com/1471-2342/12/21
_version_ 1811259903269928960
author Ringe Kristina
Ringe Bastian
von Falck Christian
Shin Hoen-oh
Becker Thomas
Pfister Eva-Doreen
Wacker Frank
Ringe Burckhardt
author_facet Ringe Kristina
Ringe Bastian
von Falck Christian
Shin Hoen-oh
Becker Thomas
Pfister Eva-Doreen
Wacker Frank
Ringe Burckhardt
author_sort Ringe Kristina
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>Living donor liver transplantation (LDLT) is a valuable and legitimate treatment for patients with end-stage liver disease. Computed tomography (CT) has proven to be an important tool in the process of donor evaluation. The purpose of this study was to evaluate the significance of CT in the donor selection process.</p> <p>Methods</p> <p>Between May 1999 and October 2010 170 candidate donors underwent biphasic CT. We retrospectively reviewed the results of the CT and liver volumetry, and assessed reasons for rejection.</p> <p>Results</p> <p>89 candidates underwent partial liver resection (52.4%). Based on the results of liver CT and volumetry 22 candidates were excluded as donors (31% of the cases). Reasons included fatty liver (n = 9), vascular anatomical variants (n = 4), incidental finding of hemangioma and focal nodular hyperplasia (n = 1) and small (n = 5) or large for size (n = 5) graft volume.</p> <p>Conclusion</p> <p>CT based imaging of the liver in combination with dedicated software plays a key role in the process of evaluation of candidates for LDLT. It may account for up to 1/3 of the contraindications for LDLT.</p>
first_indexed 2024-04-12T18:38:44Z
format Article
id doaj.art-671a70f93c474e66a49d1d639ff4af1b
institution Directory Open Access Journal
issn 1471-2342
language English
last_indexed 2024-04-12T18:38:44Z
publishDate 2012-07-01
publisher BMC
record_format Article
series BMC Medical Imaging
spelling doaj.art-671a70f93c474e66a49d1d639ff4af1b2022-12-22T03:20:51ZengBMCBMC Medical Imaging1471-23422012-07-011212110.1186/1471-2342-12-21Evaluation of living liver donors using contrast enhanced multidetector CT – The radiologists impact on donor selectionRinge KristinaRinge Bastianvon Falck ChristianShin Hoen-ohBecker ThomasPfister Eva-DoreenWacker FrankRinge Burckhardt<p>Abstract</p> <p>Background</p> <p>Living donor liver transplantation (LDLT) is a valuable and legitimate treatment for patients with end-stage liver disease. Computed tomography (CT) has proven to be an important tool in the process of donor evaluation. The purpose of this study was to evaluate the significance of CT in the donor selection process.</p> <p>Methods</p> <p>Between May 1999 and October 2010 170 candidate donors underwent biphasic CT. We retrospectively reviewed the results of the CT and liver volumetry, and assessed reasons for rejection.</p> <p>Results</p> <p>89 candidates underwent partial liver resection (52.4%). Based on the results of liver CT and volumetry 22 candidates were excluded as donors (31% of the cases). Reasons included fatty liver (n = 9), vascular anatomical variants (n = 4), incidental finding of hemangioma and focal nodular hyperplasia (n = 1) and small (n = 5) or large for size (n = 5) graft volume.</p> <p>Conclusion</p> <p>CT based imaging of the liver in combination with dedicated software plays a key role in the process of evaluation of candidates for LDLT. It may account for up to 1/3 of the contraindications for LDLT.</p>http://www.biomedcentral.com/1471-2342/12/21LDLTTransplantationLiving donorRecipientCT
spellingShingle Ringe Kristina
Ringe Bastian
von Falck Christian
Shin Hoen-oh
Becker Thomas
Pfister Eva-Doreen
Wacker Frank
Ringe Burckhardt
Evaluation of living liver donors using contrast enhanced multidetector CT – The radiologists impact on donor selection
BMC Medical Imaging
LDLT
Transplantation
Living donor
Recipient
CT
title Evaluation of living liver donors using contrast enhanced multidetector CT – The radiologists impact on donor selection
title_full Evaluation of living liver donors using contrast enhanced multidetector CT – The radiologists impact on donor selection
title_fullStr Evaluation of living liver donors using contrast enhanced multidetector CT – The radiologists impact on donor selection
title_full_unstemmed Evaluation of living liver donors using contrast enhanced multidetector CT – The radiologists impact on donor selection
title_short Evaluation of living liver donors using contrast enhanced multidetector CT – The radiologists impact on donor selection
title_sort evaluation of living liver donors using contrast enhanced multidetector ct the radiologists impact on donor selection
topic LDLT
Transplantation
Living donor
Recipient
CT
url http://www.biomedcentral.com/1471-2342/12/21
work_keys_str_mv AT ringekristina evaluationoflivingliverdonorsusingcontrastenhancedmultidetectorcttheradiologistsimpactondonorselection
AT ringebastian evaluationoflivingliverdonorsusingcontrastenhancedmultidetectorcttheradiologistsimpactondonorselection
AT vonfalckchristian evaluationoflivingliverdonorsusingcontrastenhancedmultidetectorcttheradiologistsimpactondonorselection
AT shinhoenoh evaluationoflivingliverdonorsusingcontrastenhancedmultidetectorcttheradiologistsimpactondonorselection
AT beckerthomas evaluationoflivingliverdonorsusingcontrastenhancedmultidetectorcttheradiologistsimpactondonorselection
AT pfisterevadoreen evaluationoflivingliverdonorsusingcontrastenhancedmultidetectorcttheradiologistsimpactondonorselection
AT wackerfrank evaluationoflivingliverdonorsusingcontrastenhancedmultidetectorcttheradiologistsimpactondonorselection
AT ringeburckhardt evaluationoflivingliverdonorsusingcontrastenhancedmultidetectorcttheradiologistsimpactondonorselection