Transcriptome-wide Mendelian randomization study prioritising novel tissue-dependent genes for glioma susceptibility

Transcriptome-wide Mendelian randomization study prioritising novel tissue-dependent genes for glioma susceptibility

Abstract Genome-wide association studies (GWAS) have discovered 27 loci associated with glioma risk. Whether these loci are causally implicated in glioma risk, and how risk differs across tissues, has yet to be systematically explored. We integrated multi-tissue expression quantitative trait loci (e...

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Bibliographic Details
Main Authors:	Jamie W. Robinson, Richard M. Martin, Spiridon Tsavachidis, Amy E. Howell, Caroline L. Relton, Georgina N. Armstrong, Melissa Bondy, Jie Zheng, Kathreena M. Kurian
Format:	Article
Language:	English
Published:	Nature Portfolio 2021-01-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-021-82169-5

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