Blocking iNOS and endoplasmic reticulum stress synergistically improves insulin resistance in mice

Blocking iNOS and endoplasmic reticulum stress synergistically improves insulin resistance in mice

Objective: Recent data show that iNOS has an essential role in ER stress in obesity. However, whether iNOS is sufficient to account for obesity-induced ER stress and Unfolded Protein Response (UPR) has not yet been investigated. In the present study, we used iNOS knockout mice to investigate whether...

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Bibliographic Details
Main Authors: Tamires M. Zanotto, Paula G.F. Quaresma, Dioze Guadagnini, Lais Weissmann, Andressa C. Santos, Juliana F. Vecina, Kelly Calisto, Andrey Santos, Patrícia O. Prada, Mario J.A. Saad
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877816303581

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