Establishment of iPSC (KRIBBi001-A) from CD34+ group O D-negative bone marrow blood
Human induced pluripotent stem cells with indefinite propagation in vitro provide a potential donor source of cells including erythroid cells for human therapy. Since group O D-negative (RhD−) blood cells are considered as universal donors for transfusion, it is compelling to derive iPSC line from g...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-03-01
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| Series: | Stem Cell Research |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1873506121000453 |
| _version_ | 1818870731220451328 |
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| author | Jieun Kim Hyebin Koh Xing Zhen Dong-Seok Lee Hye-Yeong Ha Jong-Hee Lee |
| author_facet | Jieun Kim Hyebin Koh Xing Zhen Dong-Seok Lee Hye-Yeong Ha Jong-Hee Lee |
| author_sort | Jieun Kim |
| collection | DOAJ |
| description | Human induced pluripotent stem cells with indefinite propagation in vitro provide a potential donor source of cells including erythroid cells for human therapy. Since group O D-negative (RhD−) blood cells are considered as universal donors for transfusion, it is compelling to derive iPSC line from group O/RhD− sample as a new cellular source to generate universal RBCs. The resulting iPSC line derived from group O/RhD− somatic source showed typical features of pluripotent stem cells and could provide an unprecedented cellular tool to develop universal therapeutics for blood transfusion. |
| first_indexed | 2024-12-19T12:11:41Z |
| format | Article |
| id | doaj.art-672286c1c62945009465a5e16a8e22c0 |
| institution | Directory Open Access Journal |
| issn | 1873-5061 |
| language | English |
| last_indexed | 2024-12-19T12:11:41Z |
| publishDate | 2021-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Stem Cell Research |
| spelling | doaj.art-672286c1c62945009465a5e16a8e22c02022-12-21T20:22:10ZengElsevierStem Cell Research1873-50612021-03-0151102199Establishment of iPSC (KRIBBi001-A) from CD34+ group O D-negative bone marrow bloodJieun Kim0Hyebin Koh1Xing Zhen2Dong-Seok Lee3Hye-Yeong Ha4Jong-Hee Lee5Futuristic Animal Resource & Research Center (FARRC), Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju, Republic of Korea; Department of Medical Life Sciences, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea; Department of Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, Seoul, Republic of KoreaFuturistic Animal Resource & Research Center (FARRC), Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju, Republic of Korea; Department of Functional Genomics, KRIBB School of Bioscience, Korea University of Science and Technology (UST), Daejeon, Republic of KoreaSchool of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu, Republic of KoreaSchool of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu, Republic of KoreaDivision of Intractable Disease Research, Korea National Institute of Health, Cheongju, Republic of Korea; Corresponding author.National Primate Research Center (NPRC), Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju, Republic of Korea; Corresponding author.Human induced pluripotent stem cells with indefinite propagation in vitro provide a potential donor source of cells including erythroid cells for human therapy. Since group O D-negative (RhD−) blood cells are considered as universal donors for transfusion, it is compelling to derive iPSC line from group O/RhD− sample as a new cellular source to generate universal RBCs. The resulting iPSC line derived from group O/RhD− somatic source showed typical features of pluripotent stem cells and could provide an unprecedented cellular tool to develop universal therapeutics for blood transfusion.http://www.sciencedirect.com/science/article/pii/S1873506121000453 |
| spellingShingle | Jieun Kim Hyebin Koh Xing Zhen Dong-Seok Lee Hye-Yeong Ha Jong-Hee Lee Establishment of iPSC (KRIBBi001-A) from CD34+ group O D-negative bone marrow blood Stem Cell Research |
| title | Establishment of iPSC (KRIBBi001-A) from CD34+ group O D-negative bone marrow blood |
| title_full | Establishment of iPSC (KRIBBi001-A) from CD34+ group O D-negative bone marrow blood |
| title_fullStr | Establishment of iPSC (KRIBBi001-A) from CD34+ group O D-negative bone marrow blood |
| title_full_unstemmed | Establishment of iPSC (KRIBBi001-A) from CD34+ group O D-negative bone marrow blood |
| title_short | Establishment of iPSC (KRIBBi001-A) from CD34+ group O D-negative bone marrow blood |
| title_sort | establishment of ipsc kribbi001 a from cd34 group o d negative bone marrow blood |
| url | http://www.sciencedirect.com/science/article/pii/S1873506121000453 |
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