Synthesis and Antimicrobial Evaluation of Certain Novel Thiazoles
Purpose: This article makes an attempt to synthesize certain compounds containing thiazole and imidazole moieties and screen for the antimicrobial properties. Methods: The novel compounds synthesized were characterized by elemental analysis, IR and 1HNMR spectral data. The antimicrobial activity of...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Tabriz University of Medical Sciences
2013-02-01
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| Series: | Advanced Pharmaceutical Bulletin |
| Subjects: | |
| Online Access: | http://journals.tbzmed.ac.ir/PDF/APB/Manuscript/APB-3-227.pdf |
| _version_ | 1818525763012395008 |
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| author | Lakshmana Rao Krishna Rao Ravindranath Yadati Narasimha Spoorthy Aluru Raghavendra Guru Prasad Meesaraganda Sreedevi |
| author_facet | Lakshmana Rao Krishna Rao Ravindranath Yadati Narasimha Spoorthy Aluru Raghavendra Guru Prasad Meesaraganda Sreedevi |
| author_sort | Lakshmana Rao Krishna Rao Ravindranath |
| collection | DOAJ |
| description | Purpose: This article makes an attempt to synthesize certain compounds containing thiazole and imidazole moieties and screen for the antimicrobial properties. Methods: The novel compounds synthesized were characterized by elemental analysis, IR and 1HNMR spectral data. The antimicrobial activity of novel compounds was evaluated by cup plate method. Results: The compound p-t showed more antibacterial activity than that of the standard. p-hp and p-as showed considerable antibacterial activity. p-t demonstrated higher antifungal activity than that of the standard while p-hp and p-as showed considerable antifungal activity. Conclusion: The antimicrobial activity studies were conducted on certain selected bacteria and fungi. In each case antimicrobial activity of the compounds was compared with that of standards. p-t, p-hp, p-np, p-cp, p-ts and p-as showed considerable antimicrobial activity. |
| first_indexed | 2024-12-11T06:13:23Z |
| format | Article |
| id | doaj.art-67238abed8714247a5d89a5755014eb0 |
| institution | Directory Open Access Journal |
| issn | 2228-5881 2251-7308 |
| language | English |
| last_indexed | 2024-12-11T06:13:23Z |
| publishDate | 2013-02-01 |
| publisher | Tabriz University of Medical Sciences |
| record_format | Article |
| series | Advanced Pharmaceutical Bulletin |
| spelling | doaj.art-67238abed8714247a5d89a5755014eb02022-12-22T01:18:03ZengTabriz University of Medical SciencesAdvanced Pharmaceutical Bulletin2228-58812251-73082013-02-0131227230http://dx.doi.org/10.5681/apb.2013.037Synthesis and Antimicrobial Evaluation of Certain Novel ThiazolesLakshmana Rao Krishna Rao RavindranathYadati Narasimha SpoorthyAluru Raghavendra Guru PrasadMeesaraganda SreedeviPurpose: This article makes an attempt to synthesize certain compounds containing thiazole and imidazole moieties and screen for the antimicrobial properties. Methods: The novel compounds synthesized were characterized by elemental analysis, IR and 1HNMR spectral data. The antimicrobial activity of novel compounds was evaluated by cup plate method. Results: The compound p-t showed more antibacterial activity than that of the standard. p-hp and p-as showed considerable antibacterial activity. p-t demonstrated higher antifungal activity than that of the standard while p-hp and p-as showed considerable antifungal activity. Conclusion: The antimicrobial activity studies were conducted on certain selected bacteria and fungi. In each case antimicrobial activity of the compounds was compared with that of standards. p-t, p-hp, p-np, p-cp, p-ts and p-as showed considerable antimicrobial activity.http://journals.tbzmed.ac.ir/PDF/APB/Manuscript/APB-3-227.pdfImidazole moietyThiazole moietySynthesisCharacterizationAntimicrobial activity |
| spellingShingle | Lakshmana Rao Krishna Rao Ravindranath Yadati Narasimha Spoorthy Aluru Raghavendra Guru Prasad Meesaraganda Sreedevi Synthesis and Antimicrobial Evaluation of Certain Novel Thiazoles Advanced Pharmaceutical Bulletin Imidazole moiety Thiazole moiety Synthesis Characterization Antimicrobial activity |
| title | Synthesis and Antimicrobial Evaluation of Certain Novel Thiazoles |
| title_full | Synthesis and Antimicrobial Evaluation of Certain Novel Thiazoles |
| title_fullStr | Synthesis and Antimicrobial Evaluation of Certain Novel Thiazoles |
| title_full_unstemmed | Synthesis and Antimicrobial Evaluation of Certain Novel Thiazoles |
| title_short | Synthesis and Antimicrobial Evaluation of Certain Novel Thiazoles |
| title_sort | synthesis and antimicrobial evaluation of certain novel thiazoles |
| topic | Imidazole moiety Thiazole moiety Synthesis Characterization Antimicrobial activity |
| url | http://journals.tbzmed.ac.ir/PDF/APB/Manuscript/APB-3-227.pdf |
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