A Retrospective Administrative Database Analysis of Suicide Attempts and Completed Suicide in Patients With Chronic Pancreatitis

Background: The actual incidence rate of suicide attempt and the suicide-related fatality rate (completed suicide) in patients with chronic pancreatitis (CP) have not been mentioned in the literature.Methods: We conducted a nationwide population-based cohort study by analyzing data from Taiwan'...

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Main Authors: Chien-Hua Chen, Cheng-Li Lin, Chung-Y. Hsu, Chia-Hung Kao
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Psychiatry
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fpsyt.2018.00147/full
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author Chien-Hua Chen
Chien-Hua Chen
Chien-Hua Chen
Chien-Hua Chen
Cheng-Li Lin
Cheng-Li Lin
Chung-Y. Hsu
Chia-Hung Kao
Chia-Hung Kao
Chia-Hung Kao
author_facet Chien-Hua Chen
Chien-Hua Chen
Chien-Hua Chen
Chien-Hua Chen
Cheng-Li Lin
Cheng-Li Lin
Chung-Y. Hsu
Chia-Hung Kao
Chia-Hung Kao
Chia-Hung Kao
author_sort Chien-Hua Chen
collection DOAJ
description Background: The actual incidence rate of suicide attempt and the suicide-related fatality rate (completed suicide) in patients with chronic pancreatitis (CP) have not been mentioned in the literature.Methods: We conducted a nationwide population-based cohort study by analyzing data from Taiwan's National Health Insurance Research Database (NHIRD) to compare the rate of suicide attempt between a CP cohort and a non-CP cohort. For the study cohort, we identified 17,733 patients (age ≥ 20 years) diagnosed as having CP between 2000 and 2010 from the NHIRD in Taiwan. Beneficiaries with no history of CP were matched with the study cohort at a 2:1 ratio according to age, sex, and index date. To determine the incidence of suicide, all patients were followed until the end of 2011 or until their withdrawal from the Taiwan National Health Insurance program.Results: Patients with CP had an increased risk of suicide attempt, compared with those without CP (adjusted hazard ratio [aHR] = 2.72, 95% confidence interval [CI] = 1.69–4.37). The suicide-related fatality in the CP cohort was higher than that in the non-CP cohort, but the difference was not statistically significant (aHR = 1.21, 95% CI = 0.39–3.78).Conclusion: Our population-based cohort study reveals a close association between CP and subsequent suicide attempt. Compared with the non-CP cohort, the suicide-related fatality was higher in the CP cohort, although the result was not statistically significant. These findings necessitate surveying patients with CP and providing psychological support to prevent suicide.
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spelling doaj.art-6723b2c80b5e421d83a78178c98c29682022-12-22T03:56:52ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402018-04-01910.3389/fpsyt.2018.00147345768A Retrospective Administrative Database Analysis of Suicide Attempts and Completed Suicide in Patients With Chronic PancreatitisChien-Hua Chen0Chien-Hua Chen1Chien-Hua Chen2Chien-Hua Chen3Cheng-Li Lin4Cheng-Li Lin5Chung-Y. Hsu6Chia-Hung Kao7Chia-Hung Kao8Chia-Hung Kao9Digestive Disease Center, Show-Chwan Memorial Hospital, Changhua, TaiwanDigestive Disease Center, Changbing Show-Chwan Memorial Hospital, Lukang, TaiwanDepartment of Food Science and Technology, Hungkuang University, Taichung, TaiwanChung Chou University of Science and Technology, Yuanlin, TaiwanManagement Office for Health Data, China Medical University Hospital, Taichung, TaiwanCollege of Medicine, China Medical University, Taichung, TaiwanGraduate Institute of Clinical Medical Science, China Medical University, Taichung, TaiwanGraduate Institute of Clinical Medical Science, School of Medicine, College of Medicine, China Medical University, Taichung, TaiwanDepartment of Nuclear Medicine and PET Center, China Medical University Hospital, Taichung, Taiwan0Department of Bioinformatics and Medical Engineering, Asia University, Taichung, TaiwanBackground: The actual incidence rate of suicide attempt and the suicide-related fatality rate (completed suicide) in patients with chronic pancreatitis (CP) have not been mentioned in the literature.Methods: We conducted a nationwide population-based cohort study by analyzing data from Taiwan's National Health Insurance Research Database (NHIRD) to compare the rate of suicide attempt between a CP cohort and a non-CP cohort. For the study cohort, we identified 17,733 patients (age ≥ 20 years) diagnosed as having CP between 2000 and 2010 from the NHIRD in Taiwan. Beneficiaries with no history of CP were matched with the study cohort at a 2:1 ratio according to age, sex, and index date. To determine the incidence of suicide, all patients were followed until the end of 2011 or until their withdrawal from the Taiwan National Health Insurance program.Results: Patients with CP had an increased risk of suicide attempt, compared with those without CP (adjusted hazard ratio [aHR] = 2.72, 95% confidence interval [CI] = 1.69–4.37). The suicide-related fatality in the CP cohort was higher than that in the non-CP cohort, but the difference was not statistically significant (aHR = 1.21, 95% CI = 0.39–3.78).Conclusion: Our population-based cohort study reveals a close association between CP and subsequent suicide attempt. Compared with the non-CP cohort, the suicide-related fatality was higher in the CP cohort, although the result was not statistically significant. These findings necessitate surveying patients with CP and providing psychological support to prevent suicide.http://journal.frontiersin.org/article/10.3389/fpsyt.2018.00147/fullchronic pancreatitissuicidecomorbiditycohort studypopulation based
spellingShingle Chien-Hua Chen
Chien-Hua Chen
Chien-Hua Chen
Chien-Hua Chen
Cheng-Li Lin
Cheng-Li Lin
Chung-Y. Hsu
Chia-Hung Kao
Chia-Hung Kao
Chia-Hung Kao
A Retrospective Administrative Database Analysis of Suicide Attempts and Completed Suicide in Patients With Chronic Pancreatitis
Frontiers in Psychiatry
chronic pancreatitis
suicide
comorbidity
cohort study
population based
title A Retrospective Administrative Database Analysis of Suicide Attempts and Completed Suicide in Patients With Chronic Pancreatitis
title_full A Retrospective Administrative Database Analysis of Suicide Attempts and Completed Suicide in Patients With Chronic Pancreatitis
title_fullStr A Retrospective Administrative Database Analysis of Suicide Attempts and Completed Suicide in Patients With Chronic Pancreatitis
title_full_unstemmed A Retrospective Administrative Database Analysis of Suicide Attempts and Completed Suicide in Patients With Chronic Pancreatitis
title_short A Retrospective Administrative Database Analysis of Suicide Attempts and Completed Suicide in Patients With Chronic Pancreatitis
title_sort retrospective administrative database analysis of suicide attempts and completed suicide in patients with chronic pancreatitis
topic chronic pancreatitis
suicide
comorbidity
cohort study
population based
url http://journal.frontiersin.org/article/10.3389/fpsyt.2018.00147/full
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