THE INVOLVEMENT OF ENDOTHELIAL DYSFUNCTION MARKERS IN THE PATHOGENESIS OF CHRONIC GLOMERULONEPHRITIS
<p><em>Chronic glomerulonephritis remains the leading cause of formation of chronic renal insufficiency, which creates the necessity of looking for new ways of the progress impediment. In the last few years considerable interest was aroused in the study of the endothelium state, especial...
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| Format: | Article |
| Language: | English |
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"Paediatrician" Publishers LLC
2006-01-01
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| Series: | Вопросы современной педиатрии |
| Subjects: | |
| Online Access: | http://vsp.spr-journal.ru:80/jour/article/view/733 |
| _version_ | 1827838718592942080 |
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| author | T.V. Margieva T.V. Sergeeva |
| author_facet | T.V. Margieva T.V. Sergeeva |
| author_sort | T.V. Margieva |
| collection | DOAJ |
| description | <p><em>Chronic glomerulonephritis remains the leading cause of formation of chronic renal insufficiency, which creates the necessity of looking for new ways of the progress impediment. In the last few years considerable interest was aroused in the study of the endothelium state, especially taking into account a wide spectrum of its physiologically important functions. The term «endothelial dysfunction» came into existence, its decisive importance in the pathogenesis of the development and progressing of the atherob sclerotic process, arterial hypertension was proven. Extensive studies are underway to establish the role of the endothelial dysfunction in case of chronic inflammatory diseases, including chronic glomerulonephritis. This article summarizes the modern views on the involvement of endothelial dysfunction markers (nitric oxide, endothelinb1, molecules of vascular cytoadherenceb1, von willebrand factor, inhibitor of plasminogenb1 activator) in the pathogenesis of chronic glomerulonephritis.</em><strong><em></em></strong><strong><em></em></strong></p><p><strong><em>Key words: endothelial dysfunction, nitric oxide, endothelin, molecule of vascular cytoadherence-1, von willebrand factor, inhibitor of plasminogen-1 activator.</em></strong></p> |
| first_indexed | 2024-03-12T07:10:12Z |
| format | Article |
| id | doaj.art-6724b9e2feb94c03830e835792ea5980 |
| institution | Directory Open Access Journal |
| issn | 1682-5527 1682-5535 |
| language | English |
| last_indexed | 2024-03-12T07:10:12Z |
| publishDate | 2006-01-01 |
| publisher | "Paediatrician" Publishers LLC |
| record_format | Article |
| series | Вопросы современной педиатрии |
| spelling | doaj.art-6724b9e2feb94c03830e835792ea59802023-09-02T23:09:16Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352006-01-01532230733THE INVOLVEMENT OF ENDOTHELIAL DYSFUNCTION MARKERS IN THE PATHOGENESIS OF CHRONIC GLOMERULONEPHRITIST.V. Margieva0T.V. Sergeeva1Scientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, Moscow<p><em>Chronic glomerulonephritis remains the leading cause of formation of chronic renal insufficiency, which creates the necessity of looking for new ways of the progress impediment. In the last few years considerable interest was aroused in the study of the endothelium state, especially taking into account a wide spectrum of its physiologically important functions. The term «endothelial dysfunction» came into existence, its decisive importance in the pathogenesis of the development and progressing of the atherob sclerotic process, arterial hypertension was proven. Extensive studies are underway to establish the role of the endothelial dysfunction in case of chronic inflammatory diseases, including chronic glomerulonephritis. This article summarizes the modern views on the involvement of endothelial dysfunction markers (nitric oxide, endothelinb1, molecules of vascular cytoadherenceb1, von willebrand factor, inhibitor of plasminogenb1 activator) in the pathogenesis of chronic glomerulonephritis.</em><strong><em></em></strong><strong><em></em></strong></p><p><strong><em>Key words: endothelial dysfunction, nitric oxide, endothelin, molecule of vascular cytoadherence-1, von willebrand factor, inhibitor of plasminogen-1 activator.</em></strong></p>http://vsp.spr-journal.ru:80/jour/article/view/733endothelial dysfunctionnitric oxideendothelinmolecule of vascular cytoadherence-1von willebrand factorinhibitor of plasminogen-1 activator |
| spellingShingle | T.V. Margieva T.V. Sergeeva THE INVOLVEMENT OF ENDOTHELIAL DYSFUNCTION MARKERS IN THE PATHOGENESIS OF CHRONIC GLOMERULONEPHRITIS Вопросы современной педиатрии endothelial dysfunction nitric oxide endothelin molecule of vascular cytoadherence-1 von willebrand factor inhibitor of plasminogen-1 activator |
| title | THE INVOLVEMENT OF ENDOTHELIAL DYSFUNCTION MARKERS IN THE PATHOGENESIS OF CHRONIC GLOMERULONEPHRITIS |
| title_full | THE INVOLVEMENT OF ENDOTHELIAL DYSFUNCTION MARKERS IN THE PATHOGENESIS OF CHRONIC GLOMERULONEPHRITIS |
| title_fullStr | THE INVOLVEMENT OF ENDOTHELIAL DYSFUNCTION MARKERS IN THE PATHOGENESIS OF CHRONIC GLOMERULONEPHRITIS |
| title_full_unstemmed | THE INVOLVEMENT OF ENDOTHELIAL DYSFUNCTION MARKERS IN THE PATHOGENESIS OF CHRONIC GLOMERULONEPHRITIS |
| title_short | THE INVOLVEMENT OF ENDOTHELIAL DYSFUNCTION MARKERS IN THE PATHOGENESIS OF CHRONIC GLOMERULONEPHRITIS |
| title_sort | involvement of endothelial dysfunction markers in the pathogenesis of chronic glomerulonephritis |
| topic | endothelial dysfunction nitric oxide endothelin molecule of vascular cytoadherence-1 von willebrand factor inhibitor of plasminogen-1 activator |
| url | http://vsp.spr-journal.ru:80/jour/article/view/733 |
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