Absence of SARS-CoV-2 antibodies in pre-pandemic plasma from children and adults in Vietnam
We tested pre-pandemic (2015–-2019) plasma samples from 148 Vietnamese children and 100 Vietnamese adults at high risk of zoonotic infections for antibodies against SARS-CoV-2 nucleocapsid and spike proteins. None was positive. The data thus demonstrated no evidence of prior serological cross-reacti...
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Format: | Article |
Language: | English |
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Elsevier
2021-10-01
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Series: | International Journal of Infectious Diseases |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S1201971221006299 |
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author | Nguyen Van Vinh Chau Le Nguyen Thanh Nhan Lam Anh Nguyet Nguyen Thi Kha Tu Nguyen Thi Thu Hong Dinh Nguyen Huy Man Dinh Thi Bich Ty Le Nguyen Truc Nhu Lam Minh Yen Truong Huu Khanh Du Tuan Quy Ngo Ngoc Quang Minh Nguyen Thi Han Ny Danielle Anderson Lin-Fa Wang H. Rogier van Doorn Nguyen Thanh Hung Tran Tan Thanh Guy Thwaites Le Van Tan |
author_facet | Nguyen Van Vinh Chau Le Nguyen Thanh Nhan Lam Anh Nguyet Nguyen Thi Kha Tu Nguyen Thi Thu Hong Dinh Nguyen Huy Man Dinh Thi Bich Ty Le Nguyen Truc Nhu Lam Minh Yen Truong Huu Khanh Du Tuan Quy Ngo Ngoc Quang Minh Nguyen Thi Han Ny Danielle Anderson Lin-Fa Wang H. Rogier van Doorn Nguyen Thanh Hung Tran Tan Thanh Guy Thwaites Le Van Tan |
author_sort | Nguyen Van Vinh Chau |
collection | DOAJ |
description | We tested pre-pandemic (2015–-2019) plasma samples from 148 Vietnamese children and 100 Vietnamese adults at high risk of zoonotic infections for antibodies against SARS-CoV-2 nucleocapsid and spike proteins. None was positive. The data thus demonstrated no evidence of prior serological cross-reactivity with SARS-CoV-2 that might explain the low numbers of COVID-19 in Vietnam. No pre-existing cross-reactivity might explain Vietnam success of COVID-19 control. |
first_indexed | 2024-12-19T00:24:01Z |
format | Article |
id | doaj.art-672af21ae5fb41f996c4818f5934dc0c |
institution | Directory Open Access Journal |
issn | 1201-9712 |
language | English |
last_indexed | 2024-12-19T00:24:01Z |
publishDate | 2021-10-01 |
publisher | Elsevier |
record_format | Article |
series | International Journal of Infectious Diseases |
spelling | doaj.art-672af21ae5fb41f996c4818f5934dc0c2022-12-21T20:45:24ZengElsevierInternational Journal of Infectious Diseases1201-97122021-10-01111127129Absence of SARS-CoV-2 antibodies in pre-pandemic plasma from children and adults in VietnamNguyen Van Vinh Chau0Le Nguyen Thanh Nhan1Lam Anh Nguyet2Nguyen Thi Kha Tu3Nguyen Thi Thu Hong4Dinh Nguyen Huy Man5Dinh Thi Bich Ty6Le Nguyen Truc Nhu7Lam Minh Yen8Truong Huu Khanh9Du Tuan Quy10Ngo Ngoc Quang Minh11Nguyen Thi Han Ny12Danielle Anderson13Lin-Fa Wang14H. Rogier van Doorn15Nguyen Thanh Hung16Tran Tan Thanh17Guy Thwaites18Le Van Tan19Hospital for Tropical Diseases, Ho Chi Minh City, VietnamChildren's Hospital 1, Ho Chi Minh City, VietnamOxford University Clinical Research Unit, Ho Chi Minh City, VietnamDong Thap Provincial Center for Disease Control, Dong Thap Province, VietnamOxford University Clinical Research Unit, Ho Chi Minh City, VietnamHospital for Tropical Diseases, Ho Chi Minh City, VietnamHospital for Tropical Diseases, Ho Chi Minh City, VietnamOxford University Clinical Research Unit, Ho Chi Minh City, VietnamOxford University Clinical Research Unit, Ho Chi Minh City, VietnamChildren's Hospital 1, Ho Chi Minh City, VietnamChildren's Hospital 1, Ho Chi Minh City, VietnamChildren's Hospital 1, Ho Chi Minh City, VietnamOxford University Clinical Research Unit, Ho Chi Minh City, VietnamDuke-NUS Medical School, SingaporeDuke-NUS Medical School, Singapore; SingHealth Duke-NUS Global Health Institute, SingaporeOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UKChildren's Hospital 1, Ho Chi Minh City, VietnamOxford University Clinical Research Unit, Ho Chi Minh City, VietnamOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UKOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam; Correspondence: Le Van TanWe tested pre-pandemic (2015–-2019) plasma samples from 148 Vietnamese children and 100 Vietnamese adults at high risk of zoonotic infections for antibodies against SARS-CoV-2 nucleocapsid and spike proteins. None was positive. The data thus demonstrated no evidence of prior serological cross-reactivity with SARS-CoV-2 that might explain the low numbers of COVID-19 in Vietnam. No pre-existing cross-reactivity might explain Vietnam success of COVID-19 control.http://www.sciencedirect.com/science/article/pii/S1201971221006299Cross-reactivitySARS-CoV-2zoonosisCOVID-19 |
spellingShingle | Nguyen Van Vinh Chau Le Nguyen Thanh Nhan Lam Anh Nguyet Nguyen Thi Kha Tu Nguyen Thi Thu Hong Dinh Nguyen Huy Man Dinh Thi Bich Ty Le Nguyen Truc Nhu Lam Minh Yen Truong Huu Khanh Du Tuan Quy Ngo Ngoc Quang Minh Nguyen Thi Han Ny Danielle Anderson Lin-Fa Wang H. Rogier van Doorn Nguyen Thanh Hung Tran Tan Thanh Guy Thwaites Le Van Tan Absence of SARS-CoV-2 antibodies in pre-pandemic plasma from children and adults in Vietnam International Journal of Infectious Diseases Cross-reactivity SARS-CoV-2 zoonosis COVID-19 |
title | Absence of SARS-CoV-2 antibodies in pre-pandemic plasma from children and adults in Vietnam |
title_full | Absence of SARS-CoV-2 antibodies in pre-pandemic plasma from children and adults in Vietnam |
title_fullStr | Absence of SARS-CoV-2 antibodies in pre-pandemic plasma from children and adults in Vietnam |
title_full_unstemmed | Absence of SARS-CoV-2 antibodies in pre-pandemic plasma from children and adults in Vietnam |
title_short | Absence of SARS-CoV-2 antibodies in pre-pandemic plasma from children and adults in Vietnam |
title_sort | absence of sars cov 2 antibodies in pre pandemic plasma from children and adults in vietnam |
topic | Cross-reactivity SARS-CoV-2 zoonosis COVID-19 |
url | http://www.sciencedirect.com/science/article/pii/S1201971221006299 |
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